Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40368 | 0.77 | CYP2C9 (0.55) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL6241456 | 0.71 | CYP2C9 (0.42) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL501810 | 0.71 | GAA (0.65) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL27927654 | 0.71 | CYP2C9 (0.49) | LMNAMAPTHTTMEN1KMT2A | |
| Phosphine SCHEMBL23295992 | 0.69 | GAA (0.63) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL2011512 | 0.68 | MAPT (0.35) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL18085321 | 0.68 | MAPT (0.53) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL25949524 | 0.68 | CYP2C9 (0.42) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL24402162 | 0.68 | GAA (0.56) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL7556279 | 0.68 | LMNA (0.46) | LMNAMAPTMAPK1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9649261-B2 | Method of applying makeup to a surface and a kit for implementing such a method | L'OREAL (FR) | 2017-05-16 | — | — | US | disclosed |
| EP-1799065-B1 | MAKE-UP METHOD USING A MAGNETIC COMPOSITION CONTAINING AT LEAST ONE TINTING AGENT HAVING OPTICAL PROPERTIES WHICH ARE SENSITIVE TO AN EXTERNAL STIMULUS | ORÉAL L (FR) | 2016-08-17 | — | — | EP | disclosed |
| US-20130160785-A1 | METHOD OF APPLYING MAKEUP TO A SURFACE AND A KIT FOR IMPLEMENTING SUCH A METHOD | L'OREAL (FR) | 2013-06-27 | — | — | US | disclosed |
| US-20080241086-A1 | Line of cosmetic compositions | L'OREAL (FR) | 2008-10-02 | — | — | US | disclosed |
| US-20080124288-A1 | Method of Applying Makeup by Means of a Magnetic Composition Incorporating at Least one Coloring Agent Having Optical Properties that are Sensitive to an External Stimulus | L"OREAL (FR) | 2008-05-29 | — | — | US | disclosed |
| EP-1923040-A2 | Cosmetic composition comprising an interferential pigment and a colouring agent which is sensitive to an external stimulus | L'OREAL (FR) | 2008-05-21 | — | — | EP | disclosed |
| US-20080102046-A1 | Cosmetic composition | L'OREAL (FR) | 2008-05-01 | — | — | US | disclosed |
| US-20080095723-A1 | Cosmetic composition | L'OREAL (FR) | 2008-04-24 | — | — | US | disclosed |
| EP-1897529-A1 | Cosmetic composition | L'OREAL (FR) | 2008-03-12 | — | — | EP | disclosed |
| EP-1897591-A2 | Cosmetic composition, in particular with iridescent effect | L'OREAL (FR) | 2008-03-12 | — | — | EP | disclosed |
| EP-1889599-A1 | Make-up composition and process for dark skin | L'OREAL (FR) | 2008-02-20 | — | — | EP | disclosed |
| US-20080019933-A1 | Method of making-up dark skin | L'OREAL (FR) | 2008-01-24 | — | — | US | disclosed |
| EP-1799065-A1 | MAKE-UP METHOD USING A MAGNETIC COMPOSITION CONTAINING AT LEAST ONE TINTING AGENT HAVING OPTICAL PROPERTIES WHICH ARE SENSITIVE TO AN EXTERNAL STIMULUS | L'Oréal (FR) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006037903-A1 | MAKE-UP METHOD USING A MAGNETIC COMPOSITION CONTAINING AT LEAST ONE TINTING AGENT HAVING OPTICAL PROPERTIES WHICH ARE SENSITIVE TO AN EXTERNAL STIMULUS | L'OREAL (FR) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080095723-A1 | Cosmetic composition | CUTA, TYR, LBR | LMNA 805/4885MAPT 1765/4885HTT 1613/4885 |
| US-20080124288-A1 | Method of Applying Makeup by Means of a Magnetic Composition Incorporating at Least one Coloring Agent Having Optical Properties that are Sensitive to an External Stimulus | KRT18, CUTA, MARK1 | LMNA 1022/4885MAPT 637/4885HTT 2687/4885 |
| US-20080241086-A1 | Line of cosmetic compositions | CUTA, TYR, RARA | LMNA 562/4885MAPT 2448/4885HTT 2315/4885 |
| US-20080019933-A1 | Method of making-up dark skin | CUTA, DSG1, TYR | LMNA 2071/4885MAPT 1929/4885HTT 1623/4885 |
| US-20080102046-A1 | Cosmetic composition | CUTA, TYR, S100A10 | LMNA 1548/4885MAPT 1033/4885HTT 659/4885 |
| US-20130160785-A1 | METHOD OF APPLYING MAKEUP TO A SURFACE AND A KIT FOR IMPLEMENTING SUCH A METHOD | CUTA, POLR1C, PRKDC | LMNA 1460/4885MAPT 1801/4885HTT 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.