Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | F7 | P08709 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10583592 | 0.85 | LMNA (0.53) | SMN1; SMN2MAPTLMNARAB9ACA2 | |
| Hydrochloric Acid SCHEMBL10590762 | 0.78 | MMP9 (0.54) | ACERAB9ANPC1CA2PTPN1 | |
| SCHEMBL7439848 | 0.78 | F10 (0.55) | MMEACECPA1ACE2F10 | |
| SCHEMBL7439860 | 0.78 | F10 (0.55) | MMEACECPA1ACE2F10 | |
| SCHEMBL10590066 | 0.77 | CYP1A2 (0.53) | ACERAB9ANPC1CA2PTPN1 | |
| SCHEMBL7275364 | 0.76 | CA2 (0.62) | ACECA2MEN1KMT2APTPN1 | |
| SCHEMBL10816310 | 0.74 | GPR132 (0.66) | MMEACECPA1ACE2SMN1; SMN2 | |
| SCHEMBL7441461 | 0.73 | PLAU (0.48) | F10MAPTRAB9APOLBF2 | |
| SCHEMBL8058939 | 0.73 | PTPN1 (0.57) | ACECA2PTPN1FPR2 | |
| Hydrochloric Acid SCHEMBL7540342 | 0.73 | FFAR1 (0.50) | MMEACECPA1ACE2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873253-A | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0284632-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1988-10-05 | — | — | EP | disclosed |