Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 3/20 | 0.39 |
| ▸ | ECE1 | P42892 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546445 | 0.95 | GAA (0.44) | RENMAPTGAAHPGDRAB9A | |
| SCHEMBL7541819 | 0.93 | ACE (0.41) | RENMAPTGAAHPGDRAB9A | |
| SCHEMBL7544077 | 0.92 | MAPK1 (0.42) | RENMAPTGAAHPGDRAB9A | |
| SCHEMBL7544754 | 0.91 | FPR2 (0.49) | RENRAB9AMMP9MMP2FPR2 | |
| SCHEMBL7546030 | 0.89 | MEN1 (0.42) | RENALDH1A1MAPTMMP2MAPK1 | |
| SCHEMBL7571304 | 0.89 | CTSK (0.41) | SMN1; SMN2RENALDH1A1MAPTGAA | |
| SCHEMBL7545886 | 0.88 | ITGB1 (0.47) | SMN1; SMN2MAPTGAAMMP9MMP2 | |
| SCHEMBL7540684 | 0.88 | GAA (0.42) | RENALDH1A1MAPTGAAHPGD | |
| SCHEMBL7542294 | 0.88 | MAPK1 (0.41) | SMN1; SMN2ALDH1A1MAPTGAAHPGD | |
| SCHEMBL7542034 | 0.86 | ITGB1 (0.47) | RENMMP9MMP2MMP8ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |