Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546445 | 0.93 | GAA (0.44) | GAAHPGDRAB9AMAPTREN | |
| SCHEMBL7546420 | 0.90 | GAA (0.43) | GAAHPGDRAB9AMAPTREN | |
| SCHEMBL7547224 | 0.88 | SMN1; SMN2 (0.41) | GAAHPGDRAB9AMAPTREN | |
| SCHEMBL7541819 | 0.88 | ACE (0.41) | GAAHPGDRAB9AMAPTREN | |
| SCHEMBL7545871 | 0.88 | RNASEL (0.43) | GAARAB9AMMP2CA1CA2 | |
| SCHEMBL7544077 | 0.88 | MAPK1 (0.42) | GAAHPGDRAB9AMAPTREN | |
| SCHEMBL7543803 | 0.86 | CTSK (0.43) | GAAHPGDRAB9AMAPTREN | |
| SCHEMBL7540893 | 0.86 | GAA (0.40) | GAAHPGDRAB9AMAPTREN | |
| SCHEMBL7544754 | 0.86 | FPR2 (0.49) | RAB9ARENMMP2MMP9MMP3 | |
| SCHEMBL7547312 | 0.86 | MMP3 (0.44) | GAAHPGDRAB9AMAPTREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |