Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805528 | 0.90 | MAPK14 (0.40) | KMOTSHRCASP1SMN1; SMN2CYP11B2 | |
| SCHEMBL7554905 | 0.84 | L3MBTL1 (0.41) | TSHRCASP1SMN1; SMN2CYP11B2KDM4E | |
| SCHEMBL7547613 | 0.83 | PYGL (0.42) | KDM4EASPHKDM8MAPK14MAPK13 | |
| SCHEMBL7553937 | 0.81 | ALDH1A1 (0.43) | TSHRCASP1SMN1; SMN2GRIK1MAPK14 | |
| SCHEMBL8802087 | 0.81 | NAPRT (0.46) | KDM4EASPHKDM8CDK2MAPK8 | |
| SCHEMBL7553546 | 0.79 | KEAP1 (0.42) | KMOKDM4EASPHKDM8MAPK14 | |
| SCHEMBL7548942 | 0.76 | KEAP1 (0.39) | KMOKDM4EASPHKDM8MAPK14 | |
| SCHEMBL27442149 | 0.76 | SMN1; SMN2 (0.48) | TSHRCASP1SMN1; SMN2CYP11B2KDM4E | |
| SCHEMBL7548594 | 0.75 | RECQL (0.48) | SMN1; SMN2MAPK14MAPK13MAPK12NAPRT | |
| SCHEMBL3426148 | 0.75 | NAPRT (0.46) | KMOKDM4EASPHKDM8NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |