Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | PRNP | P04156 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545823 | 0.88 | PDE10A (0.47) | KDM4ESMN1; SMN2ALDH1A1POLBGLA | |
| SCHEMBL7548798 | 0.80 | SMN1; SMN2 (0.42) | KDM4ESMN1; SMN2ALDH1A1POLBGLA | |
| SCHEMBL7549915 | 0.75 | PDE10A (0.41) | KDM4ESMN1; SMN2ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL26617516 | 0.74 | SMN1; SMN2 (0.67) | KDM4ESMN1; SMN2ALDH1A1POLBGLA | |
| SCHEMBL7550340 | 0.74 | PDE10A (0.41) | KDM4EALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL7550385 | 0.71 | KDM1A (0.39) | KDM4EALDH1A1CYP1A2MAPTTDP1 | |
| SCHEMBL7915032 | 0.71 | ALDH1A1 (0.56) | KDM4EALDH1A1CYP1A2MAPTMEN1 | |
| SCHEMBL852513 | 0.71 | GAA (0.50) | SMN1; SMN2POLBTDP1MEN1KMT2A | |
| SCHEMBL12267871 | 0.70 | MAPT (0.43) | KDM4EALDH1A1GLAL3MBTL1MAPT | |
| SCHEMBL852937 | 0.70 | ALDH1A1 (0.49) | KDM4EALDH1A1POLBGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046163-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTI-EPILEPTICS | WACKERNAGEL MICHAEL (DE) | 2002-06-13 | — | — | WO | claimed |
| WO-2002046163-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTI-EPILEPTICS | WACKERNAGEL MICHAEL (DE) | 2002-06-13 | — | — | WO | disclosed |