Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548608 | 0.88 | KDM4E (0.45) | PDE10AKMT2AMEN1KDM4ETSHR | |
| SCHEMBL7549915 | 0.78 | PDE10A (0.41) | PDE10AKMT2AMEN1KDM4EHTT | |
| SCHEMBL7550340 | 0.77 | PDE10A (0.41) | PDE10AKMT2AMEN1KDM4EHTT | |
| SCHEMBL7548798 | 0.75 | SMN1; SMN2 (0.42) | PDE10AKMT2AMEN1KDM4ETSHR | |
| SCHEMBL7550385 | 0.74 | KDM1A (0.39) | PDE10AKMT2AMEN1KDM4EHTT | |
| SCHEMBL7915032 | 0.74 | ALDH1A1 (0.56) | PDE10AKMT2AMEN1KDM4EHTT | |
| SCHEMBL13467803 | 0.69 | GPR3 (0.48) | PDE10AKMT2AMEN1KDM4EHTT | |
| SCHEMBL14106730 | 0.69 | PDE10A (0.72) | PDE10AKMT2AMEN1HTTTSHR | |
| SCHEMBL26617556 | 0.69 | PDE10A (0.62) | PDE10AKMT2AMEN1KDM4EHTT | |
| SCHEMBL21878637 | 0.69 | MEN1 (0.75) | PDE10AKMT2AMEN1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046163-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTI-EPILEPTICS | WACKERNAGEL MICHAEL (DE) | 2002-06-13 | — | — | WO | claimed |
| WO-2002046163-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTI-EPILEPTICS | WACKERNAGEL MICHAEL (DE) | 2002-06-13 | — | — | WO | disclosed |