Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549915 | 0.92 | PDE10A (0.41) | PDE10AALDH1A1ADORA2AKDM4EERN1 | |
| SCHEMBL7550340 | 0.79 | PDE10A (0.41) | PDE10AALDH1A1KDM4EERN1GAA | |
| SCHEMBL7915032 | 0.76 | ALDH1A1 (0.56) | PDE10AALDH1A1ADORA2AKDM4EERN1 | |
| SCHEMBL7545823 | 0.74 | PDE10A (0.47) | PDE10AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7548798 | 0.74 | SMN1; SMN2 (0.42) | PDE10AALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL13467803 | 0.71 | GPR3 (0.48) | PDE10AALDH1A1KDM4EERN1MEN1 | |
| SCHEMBL7548608 | 0.71 | KDM4E (0.45) | PDE10AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2831992 | 0.69 | APP (0.67) | ALDH1A1KDM4EMEN1KMT2AGRM5 | |
| SCHEMBL15014207 | 0.69 | APP (0.67) | ALDH1A1KDM4EMEN1KMT2AGRM5 | |
| SCHEMBL10091202 | 0.69 | APP (0.67) | ALDH1A1KDM4EMEN1KMT2AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046163-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTI-EPILEPTICS | WACKERNAGEL MICHAEL (DE) | 2002-06-13 | — | — | WO | claimed |