Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226893 | 0.86 | ALDH1A1 (0.51) | RAB9APOLBMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27772559 | 0.84 | ALDH1A1 (0.50) | RAB9APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL168448 | 0.82 | RAB9A (0.47) | GPR35TSHRRAB9APOLBMEN1 | |
| SCHEMBL168447 | 0.82 | RAB9A (0.47) | GPR35TSHRRAB9APOLBMEN1 | |
| SCHEMBL3206927 | 0.82 | GPR35 (0.55) | GPR35TSHRRAB9APOLBMEN1 | |
| SCHEMBL48359 | 0.82 | GPR35 (0.55) | GPR35TSHRRAB9APOLBMEN1 | |
| SCHEMBL28968191 | 0.81 | THRB (0.51) | RAB9APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL48360 | 0.81 | GPR35 (0.53) | GPR35TSHRRAB9APOLBMEN1 | |
| SCHEMBL48361 | 0.81 | GPR35 (0.53) | GPR35TSHRRAB9APOLBMEN1 | |
| SCHEMBL1652615 | 0.80 | GPR35 (0.51) | GPR35TSHRRAB9APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208238-A1 | METHODS OF IMMOBILIZING LIGANDS ON SOLID SUPPORTS AND APPARATUS AND METHODS OF USE THEREFOR | Mosaic Technologies (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001016372-A1 | METHODS OF IMMOBILIZING LIGANDS ON SOLID SUPPORTS AND APPARATUS AND METHODS OF USE THEREFOR | MATRIX TECHNOLOGIES CORPORATION (US) | 2001-03-08 | — | — | WO | disclosed |