Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673277 | 0.85 | TSHR (0.60) | L3MBTL1KDM4ERAB9AMEN1NPC1 | |
| SCHEMBL493397 | 0.83 | HRH1 (0.52) | KDM4ERAB9ANPC1ABCB1HTR1A | |
| SCHEMBL6489770 | 0.83 | L3MBTL1 (0.62) | L3MBTL1KDM4ERAB9ANPC1ABCB1 | |
| SCHEMBL7400760 | 0.82 | KDM4E (0.56) | KDM4ERAB9AKMT2AABCB1HTR1A | |
| Hydrochloric Acid SCHEMBL27710379 | 0.81 | SMN1; SMN2 (0.50) | L3MBTL1KDM4ERAB9ANPC1ABCB1 | |
| SCHEMBL28418292 | 0.79 | MAOB (0.50) | KDM4ERAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL27721089 | 0.79 | KDM4E (0.63) | KDM4ERAB9AABCB1HTR1ADRD2 | |
| SCHEMBL3233668 | 0.78 | L3MBTL1 (0.65) | L3MBTL1KDM4ERAB9AKCNA5MAPT | |
| SCHEMBL27683139 | 0.78 | RXRA (0.52) | RAB9ANPC1SYKLMNAPOLB | |
| SCHEMBL27683135 | 0.77 | PARP10 (0.48) | RAB9ANPC1SYKLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072567-A2 | HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2002-09-19 | — | — | WO | disclosed |