Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493397 | 0.89 | HRH1 (0.52) | ABCB1HTR1ADRD2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL27710379 | 0.87 | SMN1; SMN2 (0.50) | ABCB1HTR1ADRD2ALDH1A1KDM4E | |
| SCHEMBL7549367 | 0.85 | L3MBTL1 (0.49) | TSHRABCB1HTR1ADRD2MEN1 | |
| SCHEMBL6489770 | 0.85 | L3MBTL1 (0.62) | TSHRABCB1HTR1ADRD2ALDH1A1 | |
| SCHEMBL27683139 | 0.84 | RXRA (0.52) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| Trifluoromethanesulfonic Acid SCHEMBL15757252 | 0.83 | LMNA (0.42) | TSHRABCB1HTR1ADRD2ALDH1A1 | |
| SCHEMBL19951053 | 0.83 | ABCB1 (0.50) | TSHRABCB1HTR1ADRD2ALDH1A1 | |
| Piconol SCHEMBL7154408 | 0.83 | TSHR (0.48) | TSHRABCB1HTR1ADRD2ALDH1A1 | |
| SCHEMBL6088545 | 0.83 | DRD2 (0.43) | TSHRABCB1HTR1ADRD2ALDH1A1 | |
| SCHEMBL28418292 | 0.81 | MAOB (0.50) | ALDH1A1KMT2AKDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | claimed |
| CN-103923238-B | Catalytic component and catalyst for olefinic polymerization | 北京利和知信科技有限公司 | 2018-03-02 | — | — | CN | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| EP-0120670-B1 | IRON III COMPLEXES OF HYDROXYPYRIDONES, AND THEIR PHARMACEUTICAL COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-12-21 | — | — | EP | disclosed |
| EP-0264114-A1 | Alpha-[(phenylmethoxy)methyl]pyridine-alkanol derivatives | G.D. Searle & Co. (US) | 1988-04-20 | — | — | EP | disclosed |