Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | AGXT | P21549 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 9/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088545 | 0.83 | DRD2 (0.43) | KDM4EKMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7549367 | 0.82 | L3MBTL1 (0.49) | KDM4EIDO1AGXTSYKKMT2A | |
| SCHEMBL9673277 | 0.81 | TSHR (0.60) | KDM4EMAOBKMT2AALDH1A1MAPT | |
| SCHEMBL28344411 | 0.81 | IDO1 (0.69) | IDO1AGXTMAOBNR4A2MAOA | |
| SCHEMBL4212164 | 0.80 | KDM4E (0.61) | KDM4EIDO1AGXTKMT2AALDH1A1 | |
| SCHEMBL493397 | 0.79 | HRH1 (0.52) | KDM4EMAOBSYKALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL27710379 | 0.77 | SMN1; SMN2 (0.50) | KDM4EMAOBSYKALDH1A1MAPT | |
| SCHEMBL3922881 | 0.77 | IDO1 (0.51) | IDO1AGXTMAOBRAB9A | |
| SCHEMBL2589313 | 0.75 | KDM4E (0.56) | KDM4EKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL27663520 | 0.75 | CXCR3 (0.52) | KDM4EMAOBPTGS1SYKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072567-A2 | HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2002-09-19 | — | — | WO | disclosed |