SCHEMBL755059

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754375	0.86	FYN (0.33)	LIPGFYNMETHTTALDH1A1
	SCHEMBL752339	0.86	LIPG (0.42)	LIPGFYNMETHTTALDH1A1
	SCHEMBL754144	0.80	LIPG (0.42)	LIPGFYNHTTALDH1A1NPSR1
	SCHEMBL754314	0.77	LIPG (0.48)	LIPGPOLBRECQL
	SCHEMBL754214	0.77	LIPG (0.45)	LIPGHTTALDH1A1SMN1; SMN2
	SCHEMBL753281	0.76	LIPG (0.44)	LIPGFYNALDH1A1NPSR1SMN1; SMN2
	SCHEMBL753054	0.75	LIPG (0.39)	LIPGHTTALDH1A1SMN1; SMN2
	SCHEMBL754596	0.75	LIPG (0.42)	LIPGALDH1A1SMN1; SMN2CYP3A4
	SCHEMBL756226	0.74	NR3C2 (0.42)	LIPG
	SCHEMBL753011	0.74	JAK2 (0.45)	LIPGPOLBRECQLMCHR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.