Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508164 | 0.86 | ALDH1A1 (0.51) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7552475 | 0.84 | ALDH1A1 (0.53) | ALDH1A1CHRM2CHRM1CHRM3MMP13 | |
| SCHEMBL7515028 | 0.83 | ALDH1A1 (0.53) | ALDH1A1CHRM2MMP13MMP1MMP8 | |
| SCHEMBL7505846 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MMP13MMP1MMP8KDM4E | |
| SCHEMBL7508531 | 0.78 | ALDH1A1 (0.48) | ALDH1A1CHRM2MMP13MMP1MMP8 | |
| SCHEMBL7572878 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MMP13MMP1MMP8FKBP1A | |
| SCHEMBL7559733 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MMP13MMP1KDM4ELMNA | |
| SCHEMBL7552262 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MMP13MMP1KDM4ELMNA | |
| SCHEMBL7549978 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MMP13MMP1KDM4ELMNA | |
| SCHEMBL7509731 | 0.76 | MMP13 (0.47) | ALDH1A1MMP13MMP1KDM4EFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020006922-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | AMERICAN CYANAMID COMPANY (US) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006922-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | MMP12, ADAM33, MMP2 | ALDH1A1 3024/4885CHRM2 4668/4885CHRM4 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.