Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28341314 | 0.82 | ELANE (0.57) | KDM4EHPGDHSD17B10ELANEMAPT | |
| SCHEMBL2460415 | 0.79 | ELANE (0.54) | KDM4EHPGDHSD17B10ELANEMAPT | |
| SCHEMBL7210611 | 0.77 | MAPT (0.50) | CES1KDM4EHPGDAKR1B1HSD17B10 | |
| SCHEMBL6907008 | 0.74 | TTR (0.50) | CES1KDM4EHPGDHSD17B10ELANE | |
| SCHEMBL6254697 | 0.73 | KDM4E (0.63) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL11845702 | 0.72 | MAPT (0.53) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL11523218 | 0.72 | MAPT (0.49) | CES1KDM4EHPGDAKR1B1MAPT | |
| SCHEMBL17720783 | 0.72 | KDM4E (0.54) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL11517481 | 0.71 | AKR1B1 (0.55) | CES1KDM4EHPGDAKR1B1MAPT | |
| SCHEMBL11039554 | 0.71 | ELANE (0.55) | KDM4EHPGDHSD17B10ELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214283-A1 | PRODUCTION OF DIBENZOSUBERENONE DERIVATIVES BY CATALYTIC DEHYDROGENATION | HAARMANN & REIMER GMBH (DE) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001016065-A1 | PRODUCTION OF DIBENZOSUBERENONE DERIVATIVES BY CATALYTIC DEHYDROGENATION | HAARMANN & REIMER GMBH (DE) | 2001-03-08 | — | — | WO | disclosed |