Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56146 | 0.88 | ALDH1A1 (0.51) | BRD4ALPLALDH1A1MEN1KMT2A | |
| SCHEMBL3039804 | 0.83 | ALPL (0.48) | ALPLALDH1A1MEN1KMT2APOLB | |
| SCHEMBL17996438 | 0.82 | ALPL (0.47) | ALPLALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8632319 | 0.81 | NPC1 (0.46) | ALPLALDH1A1MEN1KMT2APOLB | |
| SCHEMBL17434495 | 0.80 | ALPL (0.48) | ALPLALDH1A1MEN1KMT2APOLB | |
| SCHEMBL2722518 | 0.77 | BRD4 (0.60) | BRD4ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL10346886 | 0.76 | MEN1 (0.59) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL29636440 | 0.76 | MEN1 (0.59) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL13574297 | 0.76 | BRD4 (0.50) | BRD4ALDH1A1POLBPDE3BPDE3A | |
| SCHEMBL17027265 | 0.76 | BRD4 (0.56) | BRD4ALDH1A1POLBPGRPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2883870-B1 | METHOD FOR PRODUCING 1,4-BENZOXAZINE COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-10-24 | — | — | EP | disclosed |
| EP-3112354-B1 | METHOD FOR PRODUCING 1,4-BENZOXAZINE COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-07-25 | — | — | EP | disclosed |
| EP-3112354-B1 | METHOD FOR PRODUCING 1,4-BENZOXAZINE COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-07-25 | — | — | EP | disclosed |
| US-9834520-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-12-05 | — | — | US | disclosed |
| US-9751846-B2 | Method for producing 1,4-benzoxazine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-09-05 | — | — | US | disclosed |
| US-9751846-B2 | Method for producing 1,4-benzoxazine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-09-05 | — | — | US | disclosed |
| EP-3112354-A1 | METHOD FOR PRODUCING 1,4-BENZOXAZINE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2017-01-04 | — | — | EP | disclosed |
| EP-3112354-A1 | METHOD FOR PRODUCING 1,4-BENZOXAZINE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20160362385-A1 | METHOD FOR PRODUCING 1,4-BENZOXAZINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2016-12-15 | — | — | US | disclosed |
| US-20160362385-A1 | METHOD FOR PRODUCING 1,4-BENZOXAZINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2016-12-15 | — | — | US | disclosed |
| US-20080300243-A1 | Amide Derivatives as Ion-Channel Ligands and Pharmaceutical Compositions and Methods of Using the Same | RENOVIS, INC. | 2008-12-04 | — | — | US | disclosed |
| EP-1984345-A1 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20080096919-A1 | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same | RENOVIS, INC. | 2008-04-24 | — | — | US | disclosed |
| US-20080096919-A1 | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same | RENOVIS, INC. | 2008-04-24 | — | — | US | disclosed |
| US-7312233-B2 | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same | RENOVIS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312233-B2 | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same | RENOVIS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| WO-2007100758-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| WO-2007089034-A1 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |
| EP-1054889-A1 | NEW OXAZOLIDINONES WITH AZOL-CONTAINING TRICYCLES | Bayer Aktiengesellschaft (DE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999040094-A1 | AGENT FOR SEALING METALLIC GROUND COATS, ESPECIALLY GROUND COATS CONSISTING OF ZINC OR ZINC ALLOYS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300243-A1 | Amide Derivatives as Ion-Channel Ligands and Pharmaceutical Compositions and Methods of Using the Same | TRPV1, TRPA1, TRPV2 | BRD4 2304/4885ALPL 2832/4885ALDH1A1 1821/4885 |
| US-20160362385-A1 | METHOD FOR PRODUCING 1,4-BENZOXAZINE COMPOUND | BRSK1, BRSK2, MSMO1 | BRD4 29/4885ALPL 3152/4885ALDH1A1 840/4885 |
| US-20080096919-A1 | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same | TRPV1, TRPA1, TRPV2 | BRD4 2304/4885ALPL 2832/4885ALDH1A1 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.