SCHEMBL755140

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752899	0.80	LIPG (0.51)	POLBALDH1A1LMNALIPG
	SCHEMBL2486832	0.78	ALDH1A1 (0.41)	POLBALDH1A1LMNALIPGMAPT
	SCHEMBL752862	0.78	LIPG (0.41)	POLBALDH1A1LMNAHPGDLIPG
	SCHEMBL752004	0.77	ALDH1A1 (0.40)	RXFP1POLBALDH1A1LMNAHPGD
	SCHEMBL751986	0.77	LIPG (0.41)	TP53POLBALDH1A1LMNAHPGD
	SCHEMBL752967	0.77	POLB (0.38)	RXFP1POLBALDH1A1LMNALIPG
	SCHEMBL754217	0.76	LIPG (0.40)	RXFP1POLBALDH1A1LMNALIPG
	SCHEMBL753133	0.76	LIPG (0.43)	TP53POLBALDH1A1LMNALIPG
	SCHEMBL18633315	0.76	POLB (0.39)	RXFP1POLBALDH1A1LMNALIPG
	SCHEMBL751187	0.76	ALDH1A1 (0.39)	RXFP1POLBALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.