⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805815 | 0.91 | CYP2C19 (0.45) | — | |
| SCHEMBL2807409 | 0.91 | HSD11B1 (0.41) | — | |
| SCHEMBL840651 | 0.89 | CYP2C19 (0.48) | — | |
| SCHEMBL3495245 | 0.89 | CYP2C19 (0.48) | — | |
| SCHEMBL3909670 | 0.87 | CYP2C19 (0.47) | — | |
| SCHEMBL14084349 | 0.79 | HSD11B1 (0.40) | — | |
| SCHEMBL17447343 | 0.78 | — | — | |
| SCHEMBL17294314 | 0.76 | LMNA (0.35) | — | |
| SCHEMBL4756992 | 0.76 | HSD11B1 (0.42) | — | |
| SCHEMBL4085736 | 0.76 | HSD11B1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019422-A1 | Cycloalkylalkanecarboxamides and their preparation and use | WETTERICH FRANK (DE) | 2002-02-14 | — | — | US | claimed |
| WO-2024204554-A1 | SPIROCYCLIC MORPHINAN DERIVATIVE | 日本ケミファ株式会社 | 2024-10-03 | — | — | WO | disclosed |
| CN-116444493-A | Derivative containing double parallel rings, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-07-18 | — | — | CN | disclosed |
| US-11661403-B2 | Oxadiazole compounds | VIVACE THERAPEUTICS, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-11453644-B1 | Compounds | ASTRAZENECA, AB (SE) | 2022-09-27 | — | — | US | disclosed |
| EP-3390396-B1 | ISOINDOLE COMPOUNDS | ASTRAZENECA AB (SE) | 2022-07-06 | — | — | EP | disclosed |
| CN-109071516-B | Novel compounds | 阿斯利康(瑞典)有限公司 | 2021-08-31 | — | — | CN | disclosed |
| US-20210238154-A1 | OXADIAZOLE COMPOUNDS | VIVACE THERAPEUTICS, INC. | 2021-08-05 | — | — | US | disclosed |
| US-10988445-B2 | Compounds | ASTRAZENECA AB (SE) | 2021-04-27 | — | — | US | disclosed |
| EP-3793551-A1 | OXADIAZOLE COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2021-03-24 | — | — | EP | disclosed |
| WO-2017102784-A9 | ISOINDOLE COMPOUNDS | ASTRAZENECA AB (SE) | 2018-04-05 | — | — | WO | disclosed |
| EP-2865664-B1 | NOVEL COMPOUND HAVING ABILITY TO INHIBIT 11B-HSD1 ENZYME OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | BAMICHEM CO LTD (KR) | 2017-11-01 | — | — | EP | disclosed |
| WO-2017102784-A1 | ISOINDOLE COMPOUNDS | ASTRAZENECA AB (SE) | 2017-06-22 | — | — | WO | disclosed |
| US-20170166527-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2017-06-15 | — | — | US | disclosed |
| US-9464044-B2 | Compound having ability to inhibit 11Beta-HSD1 enzyme or pharmaceutically acceptable salt thereof, method for producing same, and pharmaceutical composition containing same as active ingredient | AHN-GOOK PHARMACEUTICAL CO., LTD. (KR) | 2016-10-11 | — | — | US | disclosed |
| US-20150210635-A1 | NOVEL COMPOUND HAVING ABILITY TO INHIBIT 11B-HSD1 ENZYME OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION (KR) | 2015-07-30 | — | — | US | disclosed |
| EP-2865664-A1 | NOVEL COMPOUND HAVING ABILITY TO INHIBIT 11B-HSD1 ENZYME OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | BAMICHEM CO., LTD (KR) | 2015-04-29 | — | — | EP | disclosed |
| US-6410486-B2 | FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-25 | — | — | US | disclosed |
| US-20020019422-A1 | Cycloalkylalkanecarboxamides and their preparation and use | WETTERICH FRANK (DE) | 2002-02-14 | — | — | US | disclosed |
| US-6265447-B1 | FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-24 | — | — | US | disclosed |