Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840651 | 0.98 | CYP2C19 (0.48) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL3495245 | 0.98 | CYP2C19 (0.48) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL2805815 | 0.96 | CYP2C19 (0.45) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL2807409 | 0.91 | HSD11B1 (0.41) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL7552932 | 0.87 | — | — | |
| SCHEMBL5692544 | 0.79 | ALDH1A1 (0.38) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL8839908 | 0.78 | ALDH1A1 (0.37) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| Potassium Ion SCHEMBL3909671 | 0.78 | ALDH1A1 (0.37) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL14744077 | 0.77 | MCL1 (0.36) | CYP2C19ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL31119581 | 0.75 | P2RX7 (0.38) | CYP2C19ALDH1A1CYP1A2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024324-A1 | PROCESS FOR PREPARING GABAPENTIN | Pfizer Science and Technology Ireland Limited (IE) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007129286-A1 | PROCESS FOR PREPARING GABAPENTIN | PFIZER SCIENCE AND TECHNOLOGY IRELAND LIMITED (IE) | 2007-11-15 | — | — | WO | disclosed |