Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | F3 | P13726 | 2/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.55 |
| ▸ | IAPP | P10997 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751575 | 1.00 | MAOB (0.61) | MAOBAPPF3FDPSIAPP | |
| Acetone SCHEMBL22658412 | 0.92 | MAOB (0.54) | MAOBAPPF3FDPSIAPP | |
| SCHEMBL14016920 | 0.89 | IAPP (0.66) | MAOBAPPFDPSIAPPPTGS1 | |
| SCHEMBL1480903 | 0.86 | THRB (0.74) | MAOBAPPF3THRBATM | |
| SCHEMBL1480905 | 0.86 | THRB (0.74) | MAOBAPPF3THRBATM | |
| SCHEMBL872010 | 0.85 | F3 (0.75) | MAOBF3THRBATMCYP3A4 | |
| SCHEMBL872009 | 0.85 | F3 (0.75) | MAOBF3THRBATMCYP3A4 | |
| SCHEMBL26124951 | 0.85 | F3 (0.75) | MAOBF3THRBATMCYP3A4 | |
| SCHEMBL1481293 | 0.85 | TTR (0.61) | MAOBAPPF3FDPSTHRB | |
| SCHEMBL1481288 | 0.85 | TTR (0.61) | MAOBAPPF3FDPSTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223156-A1 | Use of 4-substituted 2-butanones to prepare nabumetone | HOECHST CELANESE CORPORATION (US) | 2002-07-17 | — | — | EP | claimed |
| EP-0937021-A1 | PRODUCTION OF NABUMETONE OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 1999-08-25 | — | — | EP | claimed |
| US-5907069-A | METHYLATION OF 6-BROMO-2-NAPHTHOL WITH METHYL BROMIDE OR METHYL CHLORIDE AND RECOVERING NABUMETONE | ALBEMARLE CORPORATION (US) | 1999-05-25 | — | — | US | claimed |
| EP-0892775-A2 | USE OF 4-SUBSTITUTED 2-BUTANONES TO PREPARE NABUMETONE | HOECHST CELANESE CORPORATION (US) | 1999-01-27 | — | — | EP | claimed |
| US-5847225-A | Production of naphthyl-substituted ketones from naphthaldehydes | ALBEMARLE CORPORATION (US) | 1998-12-08 | — | — | US | claimed |
| US-5756851-A | Production of nabumetone or precursors thereof | ALBEMARLE CORPORATION (US) | 1998-05-26 | — | — | US | claimed |
| WO-1998017616-A1 | PRODUCTION OF NABUMETONE OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 1998-04-30 | — | — | WO | claimed |
| US-5600009-A | Use of 4-substituted 2-butanones to prepare nabumetone | HOECHST CELANESE CORPORATION (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996040608-A2 | USE OF 4-SUBSTITUTED 2-BUTANONES TO PREPARE NABUMETONE | HOECHST CELANESE CORPORATION (US) | 1996-12-19 | — | — | WO | claimed |
| US-5225603-A | Preparation of 4-(6'-methoxy-2'-naphthyl)-3-buten-2-one | HOECHST CELANESE CORPORATION (US) | 1993-07-06 | — | — | US | claimed |
| JP-1287052-A | — | — | None | — | — | JP | disclosed |
| US-12116383-B2 | Oligosaccharide C-glycoside derivatives | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2024-10-15 | — | — | US | disclosed |
| US-20220306671-A1 | OLIGOSACCHARIDE C-GLYCOSIDE DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2022-09-29 | — | — | US | disclosed |
| US-11401293-B2 | Oligosaccharide c-glycoside derivatives | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2022-08-02 | — | — | US | disclosed |
| EP-3768693-A1 | OLIGOSACCHARIDE C-GLYCOSIDE DERIVATIVES | Okinawa Institute of Science and Technology School Corporation (JP) | 2021-01-27 | — | — | EP | disclosed |
| EP-0376516-A1 | Method of preparation of nabumetone | HOECHST CELANESE CORPORATION (US) | 1990-07-04 | — | — | EP | disclosed |
| JP-H01287052-A | NEW PRODUCTION METHOD FOR COMPOUND | BEECHAM GROUP PLC | 1989-11-17 | — | — | JP | disclosed |
| US-4426392-A | Chemical compounds | BEECHAM GROUP LIMITED (GB) | 1984-01-17 | — | — | US | disclosed |
| US-4420639-A | Aromatic compounds | BEECHAM GROUP LIMITED (GB) | 1983-12-13 | — | — | US | disclosed |
| US-4299844-A | 2-Acyloxy-4-(6-substituted-2-naphthyl)butanes | BEECHAM GROUP LIMITED (GB) | 1981-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306671-A1 | OLIGOSACCHARIDE C-GLYCOSIDE DERIVATIVES | OSTC, FUT6, FUT5 | MAOB 206/4885APP 2453/4885F3 260/4885 |
| US-11401293-B2 | Oligosaccharide c-glycoside derivatives | OSTC, FUT6, FUT5 | MAOB 206/4885APP 2453/4885F3 260/4885 |
| US-12116383-B2 | Oligosaccharide C-glycoside derivatives | OSTC, FUT6, FUT5 | MAOB 206/4885APP 2453/4885F3 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.