SCHEMBL872009

SCHEMBL872009

COc1ccc(/C=C/C(C)=O)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F3 P13726 3/20 0.75
THRB P10828 1/20 0.72
ATM Q13315 1/20 0.72
GSK3B P49841 2/20 0.70
HDAC3 O15379 2/20 0.68
HDAC1 Q13547 2/20 0.68
HDAC2 Q92769 2/20 0.68
HDAC8 Q9BY41 2/20 0.68
HDAC6 Q9UBN7 2/20 0.68
BACE1 P56817 1/20 0.64
HDAC4 P56524 1/20 0.62
HDAC7 Q8WUI4 1/20 0.62
HDAC10 Q969S8 1/20 0.62
HDAC11 Q96DB2 1/20 0.62
HDAC9 Q9UKV0 1/20 0.62
HDAC5 Q9UQL6 1/20 0.62
BCHE P06276 1/20 0.62
CYP3A4 P08684 1/20 0.62
NFKB1 P19838 1/20 0.62
NFKB2 Q00653 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL872010 1.00 F3 (0.75) F3THRBATMGSK3BHDAC3
SCHEMBL26124951 1.00 F3 (0.75) F3THRBATMGSK3BHDAC3
SCHEMBL14367145 0.94 HDAC8 (0.71) F3THRBATMGSK3BHDAC3
SCHEMBL2026113 0.87 HDAC8 (0.65) F3THRBATMGSK3BHDAC3
SCHEMBL2026112 0.87 HDAC8 (0.65) F3THRBATMGSK3BHDAC3
SCHEMBL13476143 0.86 S100B (0.63) F3THRBATMGSK3BHDAC3
SCHEMBL2744101 0.86 F3 (1.00) F3THRBATMGSK3BHDAC3
SCHEMBL14331811 0.86 F3 (1.00) F3THRBATMGSK3BHDAC3
SCHEMBL9073433 0.86 F3 (0.78) F3THRBATMGSK3BHDAC3
SCHEMBL2744098 0.86 F3 (1.00) F3THRBATMGSK3BHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034072-A1 SYNTHESIS METHOD OF NATURE-IDENTICAL RASPBERRY KEYTONE Dai, Huifang (CN) 2025-01-30 US claimed
CN-113620901-B Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof 杭州师范大学 2023-02-10 CN claimed
CN-110713436-B Method for carrying out 1, 4-conjugated reduction by photochemical catalysis of alpha, beta-ketene compound 北京工商大学 2022-06-14 CN claimed
CN-113620901-A Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof 杭州师范大学 2021-11-09 CN claimed
CN-101717328-B New method for synthesizing raspberry ketone by using natural equivalent anisic aldehyde GUANGXI WANSHAN ANISE CO LTD 2014-09-24 CN claimed
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 EP claimed
CN-101717328-A New method for synthesizing raspberry ketone by using natural equivalent anisic aldehyde GUANGXI WANSHAN ANISE CO LTD 2010-06-02 CN claimed
US-7413579-B2 Method for dyeing fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-19 US claimed
EP-1534227-B1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KGAA (DE) 2006-12-27 EP claimed
US-20060265818-A1 At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections HENKEL KOMMANDITGESELLSCHAFT AUF AKLLEN (HENKEL KGAA) (DE) 2006-11-30 US claimed
EP-1433469-B1 Composition for dyeing keratinous fibres HENKEL KGAA (DE) 2006-10-11 EP claimed
US-7105032-B2 Agents used for dyeing keratinous fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-09-12 US claimed
EP-1434557-B1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KGAA (DE) 2005-11-09 EP claimed
US-20050144740-A1 Agents used for dyeing keratinous fibers HENKEL AG & CO. KGAA (DE) 2005-07-07 US claimed
CN-122038326-A Perakine reductase mutant and application thereof in double bond reduction 浙江大学 2026-05-15 CN disclosed
EP-4727923-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA University of Georgia Research Foundation, Inc. (US) 2026-04-22 EP disclosed
US-20260098012-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA UNIV GEORGIA (US) 2026-04-09 US disclosed
US-4005147-A Production of α,β-unsaturated ketones BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1977-01-25 US disclosed
US-3989708-A HYPOTENSIVE, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-11-02 US disclosed
US-3987200-A INOTROPIC AGENTS, 3,4-DIHYDROXY-PHENYL-ALKYL PHENETHYLAMINE ELI LILLY AND COMPANY (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050144740-A1 Agents used for dyeing keratinous fibers KRT18, TUBB3, DSG1 F3 3351/4885THRB 4150/4885ATM 3428/4885
US-20260098012-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA CD47, SLC11A2, G6PD F3 898/4885THRB 2332/4885ATM 718/4885
US-20060265818-A1 At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections KRT18, CUTA, PLOD2 F3 3994/4885THRB 3492/4885ATM 3687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.