SCHEMBL872010

SCHEMBL872010

COc1ccc(C=CC(C)=O)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F3 P13726 3/20 0.75
THRB P10828 1/20 0.72
ATM Q13315 1/20 0.72
GSK3B P49841 2/20 0.70
HDAC3 O15379 2/20 0.68
HDAC1 Q13547 2/20 0.68
HDAC2 Q92769 2/20 0.68
HDAC8 Q9BY41 2/20 0.68
HDAC6 Q9UBN7 2/20 0.68
BACE1 P56817 1/20 0.64
HDAC4 P56524 1/20 0.62
HDAC7 Q8WUI4 1/20 0.62
HDAC10 Q969S8 1/20 0.62
HDAC11 Q96DB2 1/20 0.62
HDAC9 Q9UKV0 1/20 0.62
HDAC5 Q9UQL6 1/20 0.62
BCHE P06276 1/20 0.62
CYP3A4 P08684 1/20 0.62
NFKB1 P19838 1/20 0.62
NFKB2 Q00653 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL872009 1.00 F3 (0.75) F3THRBATMGSK3BHDAC3
SCHEMBL26124951 1.00 F3 (0.75) F3THRBATMGSK3BHDAC3
SCHEMBL14367145 0.94 HDAC8 (0.71) F3THRBATMGSK3BHDAC3
SCHEMBL2026113 0.87 HDAC8 (0.65) F3THRBATMGSK3BHDAC3
SCHEMBL2026112 0.87 HDAC8 (0.65) F3THRBATMGSK3BHDAC3
SCHEMBL13476143 0.86 S100B (0.63) F3THRBATMGSK3BHDAC3
SCHEMBL2744101 0.86 F3 (1.00) F3THRBATMGSK3BHDAC3
SCHEMBL14331811 0.86 F3 (1.00) F3THRBATMGSK3BHDAC3
SCHEMBL9073433 0.86 F3 (0.78) F3THRBATMGSK3BHDAC3
SCHEMBL2744098 0.86 F3 (1.00) F3THRBATMGSK3BHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034072-A1 SYNTHESIS METHOD OF NATURE-IDENTICAL RASPBERRY KEYTONE Dai, Huifang (CN) 2025-01-30 US claimed
CN-119120338-A Prostaglandin reductase and glucose dehydrogenase co-expression recombinant bacterium and application thereof 淮阴工学院 2024-12-13 CN claimed
CN-118255708-A Polysubstituted carbazole derivative and synthesis method thereof 重庆理工大学 2024-06-28 CN claimed
CN-116043244-A Method for preparing alpha, beta-unsaturated ketone by electrocatalytic oxidation of alcohol 北京化工大学 2023-05-02 CN claimed
CN-113620901-B Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof 杭州师范大学 2023-02-10 CN claimed
CN-113620901-A Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof 杭州师范大学 2021-11-09 CN claimed
CN-111675728-B Fluorescent probe based on phenylselenol group specific response Cys, preparation method and application 河南大学 2021-04-20 CN claimed
CN-111675728-A Fluorescent probe based on phenylselenol group specific response Cys, preparation method and application 河南大学 2020-09-18 CN claimed
CN-101717328-B New method for synthesizing raspberry ketone by using natural equivalent anisic aldehyde GUANGXI WANSHAN ANISE CO LTD 2014-09-24 CN claimed
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 EP claimed
CN-1681470-A Agent for dyeing keratinous fibres HENKEL KGAA (DE) 2005-10-12 CN claimed
WO-2005063178-A1 AGENTS FOR COLOURING FIBRES CONTAINING KERATIN, COMPRISING HETEROCYCLIC ENAMINES AND REACTIVE CARBONYL COMPOUNDS AND/OR REACTION PRODUCTS THEREOF HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-07-14 WO claimed
US-20050144740-A1 Agents used for dyeing keratinous fibers HENKEL AG & CO. KGAA (DE) 2005-07-07 US claimed
WO-2005051336-A1 METHOD FOR DYEING FIBRES CONTAINING KERATINE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-06-09 WO claimed
EP-1534227-A1 AGENTS USED FOR DYEING KERATINOUS FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2005-06-01 EP claimed
EP-1434557-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2004-07-07 EP claimed
EP-1433469-A1 Composition for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
WO-2004022016-A1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-03-18 WO claimed
WO-2003030845-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-0873743-A2 Use of benzylidene-ketones for dyeing keratinous fibers Henkel Kommanditgesellschaft auf Aktien (DE) 1998-10-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050144740-A1 Agents used for dyeing keratinous fibers KRT18, TUBB3, DSG1 F3 3351/4885THRB 4150/4885ATM 3428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.