Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533293 | 0.86 | KDM4E (0.36) | KDM4EGAAPTGDR2PTGDRLTB4R | |
| SCHEMBL10584739 | 0.85 | ALOX5 (0.34) | PTGDR2PTGDRLTB4RALDH1A1POLB | |
| SCHEMBL10424599 | 0.81 | AKR1B1 (0.43) | KDM4EPTGDR2LTB4RALDH1A1PPARG | |
| SCHEMBL15380492 | 0.80 | LTB4R (0.47) | KDM4EPTGDR2LTB4RALDH1A1PPARG | |
| SCHEMBL1164626 | 0.79 | GABRA1 (0.36) | POLBGABRA1GABRB2 | |
| SCHEMBL4600787 | 0.78 | PTGDR2 (0.41) | KDM4EPTGDR2LTB4RALDH1A1PPARG | |
| SCHEMBL7556328 | 0.78 | GABRA1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL11345353 | 0.77 | ALDH1A1 (0.40) | KDM4EPTGDR2LTB4RALDH1A1PPARG | |
| SCHEMBL31564493 | 0.75 | KDM4E (0.38) | KDM4EGAAPTGDR2LTB4RALDH1A1 | |
| SCHEMBL29882 | 0.75 | PTPRC (0.42) | PTGDR2PTGDRKMT2AGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002020366-A | METHOD FOR PRODUCING ALKYLTHIOPHENYLACETIC ACID | SUMITOMO SEIKA CHEM CO LTD | 2002-01-23 | — | — | JP | disclosed |
| US-3969401-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | WILLIAM H. RORER, INC. (US) | 1976-07-13 | — | — | US | disclosed |