Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7556532 | 0.86 | KDM4E (0.39) | KDM4EGAALTB4RAKR1B1PTGDR2 | |
| SCHEMBL10424599 | 0.81 | AKR1B1 (0.43) | KDM4ELTB4RAKR1B1PTGDR2KMT2A | |
| SCHEMBL1164626 | 0.79 | GABRA1 (0.36) | — | |
| SCHEMBL15532895 | 0.79 | PKM (0.39) | KDM4EGAAKMT2AMEN1HSD17B10 | |
| SCHEMBL15604516 | 0.77 | ALDH1A1 (0.41) | KDM4EGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL367774 | 0.77 | AKR1B1 (0.39) | LTB4RAKR1B1PTGDR2KMT2AALDH1A1 | |
| SCHEMBL11636866 | 0.77 | KEAP1 (0.40) | KDM4ELTB4RAKR1B1PTGDR2KMT2A | |
| SCHEMBL3801503 | 0.75 | KMT2A (0.40) | KDM4EGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL10584739 | 0.75 | ALOX5 (0.34) | LTB4RPTGDR2PTGDRKMT2AMEN1 | |
| SCHEMBL11661785 | 0.72 | LTB4R (0.36) | GAALTB4RAKR1B1PTGDR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134726-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-17 | — | — | US | disclosed |
| US-20180134726-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-17 | — | — | US | disclosed |
| US-20180134726-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-17 | — | — | US | disclosed |
| EP-2854541-B1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-15 | — | — | EP | disclosed |
| EP-2854541-B1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-15 | — | — | EP | disclosed |
| EP-2854541-A1 | PLANT GROWTH REGULATING COMPOUNDS | Syngenta Participations AG (CH) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013174846-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-28 | — | — | WO | disclosed |
| WO-2013174846-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134726-A1 | PLANT GROWTH REGULATING COMPOUNDS | GHITM, GHDC, AREG | KDM4E 3395/4885GAA 1203/4885LTB4R 3273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.