SCHEMBL755658

SCHEMBL755658

O=[PH](O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.46
BCL2L1 Q07817 1/20 0.46
ALDH1A1 P00352 2/20 0.45
ALOX5 P09917 1/20 0.44
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
WDR5 P61964 1/20 0.43
HNF4A P41235 1/20 0.42
ACMSD Q8TDX5 1/20 0.42
ABCC4 O15439 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
PTGS1 P23219 1/20 0.41
HTT P42858 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
MGLL Q99685 1/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL9807554 0.92 ALDH1A1 (0.47) MMP3BCL2L1ALDH1A1MAPTSMN1; SMN2
SCHEMBL11660419 0.91 KMO (0.48) ALOX5HNF4AACMSDMGLLRAB9A
SCHEMBL7705345 0.89 ESR1 (0.35) ALOX5
Sulfur Dioxide SCHEMBL28692326 0.86 MMP3 (0.37) MMP3BCL2L1ALDH1A1MAPTSMN1; SMN2
SCHEMBL36107 0.84
SCHEMBL23780657 0.81 TSHR (0.38) ALDH1A1MAPTSMN1; SMN2ACMSDTSHR
SCHEMBL17891672 0.81 TSHR (0.35) ALDH1A1MAPTSMN1; SMN2ACMSDTSHR
SCHEMBL285639 0.81 TSHR (0.35) ALDH1A1MAPTSMN1; SMN2ACMSDTSHR
SCHEMBL3950153 0.81 TSHR (0.35) ALDH1A1MAPTSMN1; SMN2ACMSDTSHR
SCHEMBL640311 0.81 TSHR (0.35) ALDH1A1MAPTSMN1; SMN2ACMSDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586304-A Aryl phosphonate and aryl thiophosphonate compound and preparation method thereof 烟台大学 2024-02-23 CN claimed
US-5245005-A Amine end groups, phosphinic acid catalyst MONSANTO COMPANY (US) 1993-09-14 US claimed
CN-117586304-A Aryl phosphonate and aryl thiophosphonate compound and preparation method thereof 烟台大学 2024-02-23 CN disclosed
US-8476372-B2 Polyester fiber and method for its production, and tire cord, tire, belt-reinforcing fiber material and belt comprising the polyester fiber TEIJIN FIBERS LIMITED (JP) 2013-07-02 US disclosed
US-8383609-B2 Phosphorus containing heterocyclic compounds, sugar analogues, and compositions having anti-cancer activity containing the same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-02-26 US disclosed
EP-2258891-B1 POLYETHYLENE NAPHTHALATE FIBER AND PROCESS FOR PRODUCING THE POLYETHYLENE NAPHTHALATE FIBER TEIJIN FIBERS LTD (JP) 2012-12-12 EP disclosed
EP-2253747-B1 POLYETHYLENE NAPHTHALATE FIBER AND PROCESS FOR PRODUCING THE POLYETHYLENE NAPHTHALATE FIBER TEIJIN FIBERS LTD (JP) 2012-11-07 EP disclosed
US-8163841-B2 Polyethylene naphthalate fibers and method for producing the same TEIJIN FIBERS LIMITED (JP) 2012-04-24 US disclosed
US-8158718-B2 Polyethylene naphthalate fibers and method for producing the same TEIJIN FIBERS LIMITED (JP) 2012-04-17 US disclosed
EP-2261403-B1 POLYESTER FIBER, PROCESS FOR PRODUCING THE POLYESTER FIBER, AND TIRE CODE, TIRE, FIBER MATERIAL FOR REINFORCING BELT AND BELT EACH COMPRISING THE POLYESTER FIBER TEIJIN FIBERS LTD (JP) 2012-03-21 EP disclosed
US-20110040009-A1 POLYETHYLENE NAPHTHALATE FIBERS AND METHOD FOR PRODUCING THE SAME TEIJIN FIBERS LIMITED (JP) 2011-02-17 US disclosed
US-20110017378-A1 POLYESTER FIBER AND METHOD FOR ITS PRODUCTION, AND TIRE CORD, TIRE, BELT-REINFORCING FIBER MATERIAL AND BELT COMPRISING THE POLYESTER FIBER TEIJIN FIBERS LIMITED (JP) 2011-01-27 US disclosed
US-20110015326-A1 POLYETHYLENE NAPHTHALATE FIBERS AND METHOD FOR PRODUCING THE SAME TEIJIN FIBERS LIMITED (JP) 2011-01-20 US disclosed
EP-2261403-A1 POLYESTER FIBER, PROCESS FOR PRODUCING THE POLYESTER FIBER, AND TIRE CODE, TIRE, FIBER MATERIAL FOR REINFORCING BELT AND BELT EACH COMPRISING THE POLYESTER FIBER Teijin Fibers Limited (JP) 2010-12-15 EP disclosed
EP-2258891-A1 POLYETHYLENE NAPHTHALATE FIBER AND PROCESS FOR PRODUCING THE POLYETHYLENE NAPHTHALATE FIBER Teijin Fibers Limited (JP) 2010-12-08 EP disclosed
US-20100298272-A1 PHOSPHORUS CONTAINING HETEROCYCLIC COMPOUNDS, SUGAR ANALOGUES, AND COMPOSITIONS HAVING ANTI-CANCER ACTIVITY CONTAINING THE SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-11-25 US disclosed
EP-2253747-A1 POLYETHYLENE NAPHTHALATE FIBER AND PROCESS FOR PRODUCING THE POLYETHYLENE NAPHTHALATE FIBER Teijin Fibers Limited (JP) 2010-11-24 EP disclosed
US-5245005-A Amine end groups, phosphinic acid catalyst MONSANTO COMPANY (US) 1993-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298272-A1 PHOSPHORUS CONTAINING HETEROCYCLIC COMPOUNDS, SUGAR ANALOGUES, AND COMPOSITIONS HAVING ANTI-CANCER ACTIVITY CONTAINING THE SAME G6PC1, SLC5A1, HK1 MMP3 2181/4885BCL2L1 1593/4885ALDH1A1 1837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.