SCHEMBL755779

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14848166	0.79	LIPG (0.78)	LIPGTP53HTTLMNAGAA
	SCHEMBL755373	0.75	CTSD (0.45)	LIPGSMN1; SMN2ALDH1A1LMNAGAA
	SCHEMBL14046287	0.74	SMN1; SMN2 (0.45)	SMN1; SMN2HTTTDP1EGFRERBB2
	SCHEMBL753326	0.73	LIPG (0.46)	LIPGTP53HTTALDH1A1LMNA
	SCHEMBL13255479	0.72	EGLN1 (0.47)	SMN1; SMN2HTTKMT2AMEN1GAA
	SCHEMBL753149	0.71	MEN1 (0.44)	SMN1; SMN2ALDH1A1KMT2ALMNAMEN1
	SCHEMBL13255399	0.71	SMN1; SMN2 (0.42)	SMN1; SMN2TP53HTTALDH1A1KMT2A
	SCHEMBL13255388	0.71	SMN1; SMN2 (0.42)	SMN1; SMN2HTTTDP1ALDH1A1EGFR
	SCHEMBL13255457	0.71	SMN1; SMN2 (0.42)	SMN1; SMN2HTTALDH1A1EGFRERBB2
	SCHEMBL12266075	0.70	LMNA (0.46)	SMN1; SMN2ALDH1A1LMNAPLAUELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.