SCHEMBL753149

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752325	0.72	KDM1A (0.51)	MEN1KMT2AUSP2ALDH1A1KDM4E
	SCHEMBL16925510	0.72	ALDH1A1 (0.52)	MEN1KMT2APLAUELANESMN1; SMN2
	SCHEMBL755779	0.71	LIPG (0.48)	MEN1KMT2APLAUELANESMN1; SMN2
	SCHEMBL752911	0.69	ALDH1A1 (0.57)	KMT2ASMN1; SMN2LMNAALDH1A1KDM4E
	SCHEMBL12266076	0.68	SMN1; SMN2 (0.42)	KMT2ASMN1; SMN2USP2LMNAALDH1A1
	SCHEMBL24439856	0.67	KMT2A (0.63)	MEN1KMT2ABRD4SMN1; SMN2USP2
	SCHEMBL29606010	0.67	KMT2A (0.63)	MEN1KMT2ABRD4SMN1; SMN2USP2
	SCHEMBL754735	0.67	SMN1; SMN2 (0.43)	MEN1KMT2ASMN1; SMN2RAB9AHPGD
	SCHEMBL12266075	0.65	LMNA (0.46)	PLAUELANESMN1; SMN2USP2LMNA
	SCHEMBL13255479	0.64	EGLN1 (0.47)	MEN1KMT2ASMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.