Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.38 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5436825 | 0.98 | NAPRT (0.39) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL2263489 | 0.82 | NR1I2 (0.42) | CYP1A2CYP3A4CYP2D6CYP2C19KMT2A | |
| SCHEMBL11758909 | 0.81 | KMT2A (0.40) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7560833 | 0.79 | HDAC3 (0.45) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6522858 | 0.78 | NAPRT (0.42) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9365632 | 0.77 | NAPRT (0.38) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| Bromide SCHEMBL11344288 | 0.77 | HDAC3 (0.44) | CYP1A2CYP3A4CYP2D6CYP2C19KMT2A | |
| SCHEMBL2172789 | 0.76 | NAPRT (0.41) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23176316 | 0.76 | MAOA (0.40) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4629983 | 0.76 | NAAA (0.50) | CYP1A2CYP3A4CYP2D6CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107847498-A | tetra-substituted olefin compound and use thereof | 卫材R&D管理有限公司 | 2018-03-27 | — | — | CN | claimed |
| CN-109534317-B | Preparation method of carbon nanotube film | 中国科学院物理研究所 | 2021-11-23 | — | — | CN | disclosed |
| EP-2927253-B1 | ORGANOPOLYSILOXANE GRAFT POLYMER | KAO CORP (JP) | 2018-09-12 | — | — | EP | disclosed |
| US-9351920-B2 | Organopolysiloxane graft polymer | KAO CORPORATION (JP) | 2016-05-31 | — | — | US | disclosed |
| US-20150297498-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | KAO CORPORATION (JP) | 2015-10-22 | — | — | US | disclosed |
| EP-2927253-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | Kao Corporation (JP) | 2015-10-07 | — | — | EP | disclosed |
| CN-1379777-A | Amino-triazolopyridine derivatives | HOFFMANN LA ROCHE (CH) | 2002-11-13 | — | — | CN | disclosed |
| EP-1227111-A1 | TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF | Yoshitomi Fine Chemicals, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |
| WO-1996036683-A1 | MIXED PHOSPHOROUS- AND SULFUR-CONTAINING REACTION PRODUCTS USEFUL IN POWER TRANSMITTING COMPOSITIONS | EXXON CHEMICAL PATENTS INC. (US) | 1996-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297498-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | IDUA, PIGS, GMNN | NAPRT 3499/4885CYP1A2 3979/4885CYP3A4 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.