Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL8011646 | 0.86 | MAPT (0.44) | MAPTMEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL5159677 | 0.83 | ALDH1A1 (0.40) | MAPTCYP3A4ALDH1A1KDM5AKDM5B | |
| SCHEMBL252910 | 0.66 | PTGS2 (0.52) | MAPTMEN1KMT2ACYP2C19MAPK1 | |
| SCHEMBL28348142 | 0.65 | CA2 (0.57) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| Phosphonic Acid SCHEMBL5668726 | 0.65 | MAPT (0.37) | MAPTMEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL7368290 | 0.65 | CA2 (0.45) | MAPTMEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL7668780 | 0.65 | ALDH1A1 (0.47) | MAPTMEN1KMT2ACYP2C19MAPK1 | |
| SCHEMBL17720551 | 0.64 | CA1 (0.30) | — | |
| SCHEMBL2614593 | 0.64 | S1PR1 (0.42) | MAPTIDO1MRGPRX4 | |
| SCHEMBL25682539 | 0.64 | ALDH1A1 (0.54) | MAPTMEN1KMT2ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019390-B1 | 1,2 CHEMILUMINESCENT DIOXETANES OF IMPROVED PERFORMANCE | TROPIX INC (US) | 2002-07-24 | — | — | EP | disclosed |
| US-5981768-A | SUITABLE FOR USE IN A WIDE VARIETY OF ASSAYS AND OTHER DETECTION APPLICATIONS | TROPIX, INC. (US) | 1999-11-09 | — | — | US | disclosed |
| US-5869699-A | STABLE DIOXETANE BEARING A SPIROADAMANTANE STABILIZING GROUP AND ARYLOXY MOIETY, WITH A PROTECTING GROUP THAT CAN BE REMOVED BY AN ENZYMATIC OR CHEMICAL TRIGGER; KIT FOR USE IN ASSAYS REQUIRING HIGH LIGHT INTENSITY, DETECTION SENSITIVITY | TROPIX, INC. (US) | 1999-02-09 | — | — | US | disclosed |
| US-5847161-A | 1, 2 chemiluminescent dioxetanes of improved performance | TROPIX, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| US-5679803-A | 1,2 chemiluminescent dioxetanes of improved performance | TROPIX, INC. (US) | 1997-10-21 | — | — | US | disclosed |