Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.38 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.37 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.35 |
| ▸ | RHOC | P08134 | 1/20 | 0.35 |
| ▸ | RHOA | P61586 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989035 | 0.77 | KCNJ11 (0.46) | TAS2R14RXFP1DDR1LMNAUSP36 | |
| SCHEMBL6989037 | 0.76 | DDR1 (0.43) | TAS2R14RXFP1DDR1LMNAPOLB | |
| SCHEMBL6982554 | 0.76 | TAS2R14 (0.39) | TAS2R14RXFP1MAPKAPK2DDR1LMNA | |
| SCHEMBL7559454 | 0.69 | TAS2R14 (0.37) | TAS2R14DDR1GAAUSP36CYP3A4 | |
| SCHEMBL7559839 | 0.68 | RHOC (0.39) | DDR1LMNAGAAUSP36RHOC | |
| SCHEMBL30728660 | 0.67 | P2RX1 (0.70) | TAS2R14RXFP1LMNAGAAP2RX1 | |
| SCHEMBL7092768 | 0.64 | TAS2R14 (0.47) | TAS2R14CYP3A4CYP2C9SLC22A6SLC22A8 | |
| SCHEMBL3835811 | 0.63 | POLB (0.56) | LMNAPOLBGAAUSP36 | |
| SCHEMBL27070948 | 0.62 | NAMPT (0.56) | RXFP1DDR1EPHB2DDR2USP36 | |
| SCHEMBL30728722 | 0.62 | NAMPT (0.56) | RXFP1DDR1EPHB2DDR2USP36 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020165264-A1 | Aminal diones as potassium channel openers | ABBOTT LABORATORIES | 2002-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165264-A1 | Aminal diones as potassium channel openers | KCNJ2, KCNJ11, KCNH1 | TAS2R14 2840/4885RXFP1 2600/4885MAPKAPK2 2283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.