Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | RHOC | P08134 | 4/20 | 0.39 |
| ▸ | RHOA | P61586 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981925 | 0.83 | NAMPT (0.50) | MAPTMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL6990741 | 0.83 | GABRA5 (0.35) | DDR1PPARDMAPTMEN1KMT2A | |
| SCHEMBL6990809 | 0.79 | MEN1 (0.48) | MAPTMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL6989035 | 0.79 | KCNJ11 (0.46) | DDR1TAS2R14RHOCRHOAUSP36 | |
| SCHEMBL7559161 | 0.76 | TAS2R14 (0.43) | DDR1TAS2R14RHOCRHOAUSP36 | |
| SCHEMBL4367794 | 0.76 | GRM5 (0.45) | MAPTMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL6990458 | 0.76 | CSF1R (0.44) | MAPTMEN1KMT2ALMNANPC1 | |
| SCHEMBL6989465 | 0.76 | NPC1 (0.41) | PPARDMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL6986333 | 0.75 | MEN1 (0.48) | MAPTMEN1KMT2AGAAPOLB | |
| SCHEMBL6982554 | 0.74 | TAS2R14 (0.39) | DDR1TAS2R14USP36RXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358160-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | claimed |
| WO-2002062761-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | claimed |