SCHEMBL755983

SCHEMBL755983

OC(CCC(O)(O)O)c1cnc(C(O)CCC(O)(O)O)cn1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706462 0.85 KDM4E (0.34) RIPK1
SCHEMBL13349600 0.66 RIPK1 (0.35) RIPK1
SCHEMBL12091514 0.66 LMNA (0.31)
SCHEMBL3297238 0.62 PYGL (0.34)
SCHEMBL12200519 0.61 SMO (0.34)
SCHEMBL17077854 0.61
SCHEMBL16862140 0.60 PLA2G7 (0.35) RIPK1
SCHEMBL16861838 0.60 CYP2C19 (0.42) RIPK1
SCHEMBL2737003 0.59 RIPK1 (0.59) RIPK1
SCHEMBL9491351 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9592202-B2 Method to stabilize a dietary supplement to facilitate joint health in humans WYETH LLC (US) 2017-03-14 US disclosed
EP-2429500-B1 METHOD TO STABILIZE A DIETARY SUPPLEMENT COMPRISING GLUCOSAMINE WYETH LLC (US) 2015-01-14 EP disclosed
EP-2429500-A1 METHOD TO STABILIZE A DIETARY SUPPLEMENT COMPRISING GLUCOSAMINE Wyeth LLC (US) 2012-03-21 EP disclosed
WO-2010141191-A1 METHOD TO STABILIZE A DIETARY SUPPLEMENT COMPRISING GLUCOSAMINE WYETH LLC (US) 2010-12-09 WO disclosed
US-20100291240-A1 Method to Stabilize a Dietary Supplement to Facilitate Joint Health in Humans WYETH LLC (US) 2010-11-18 US disclosed
EP-1704862-A1 2,5-bis(tetrahydroxybutyl)pyrazines for the treatment of osteoarthritis and rheumatoid arthritis Rottapharm S.p.A. (IT) 2006-09-27 EP disclosed
EP-1704862-A1 2,5-bis(tetrahydroxybutyl)pyrazines for the treatment of osteoarthritis and rheumatoid arthritis Rottapharm S.p.A. (IT) 2006-09-27 EP disclosed
US-20020051828-A1 Mixtures which can be isolated from eugenia jambolana lamarck seeds, their preparation and the use of these mixtures and some of their constituents as medicaments RHONE-POULENC RORER S.A. AND INSTITUT MALGACHE DE RECHERCHES APPLIQUEES 2002-05-02 US disclosed
US-6300375-B1 ADMINISTERING SODIUM OXAMATE FOR PROPHYLAXIS OR THERAPY OF DIABETES OR COMPLICATIONS DUE TO DIABETES RHONE-POULENC RORER SA (FR) 2001-10-09 US disclosed
EP-0879058-B1 MIXTURES DERIVED FROM GRAINS OF EUGENIA JAMBOLANA LAMARCK, PREPARATION AND USE OF SAID MIXTURES AND SOME OF THEIR CONSTITUENTS AS MEDICAMENTS INST MALGACHE DE RECH S APPLIQ (MG) 2001-06-06 EP disclosed
US-6194412-B1 ANTIDIABETIC AGENTS RHONE-POULENC RORER S.A. (FR) 2001-02-27 US disclosed
US-5972342-A ANTIDIABETIC AGENTS RHONE-POULENC RORER S.A. (FR) 1999-10-26 US disclosed
EP-0879058-A1 MIXTURES DERIVED FROM GRAINS OF EUGENIA JAMBOLANA LAMARCK, PREPARATION AND USE OF SAID MIXTURES AND SOME OF THEIR CONSTITUENTS AS MEDICAMENTS Institut Malgache de Recherches Appliquées (MG) 1998-11-25 EP disclosed
WO-1997028813-A1 MIXTURES DERIVED FROM GRAINS OF EUGENIA JAMBOLANA LAMARCK, PREPARATION AND USE OF SAID MIXTURES AND SOME OF THEIR CONSTITUENTS AS MEDICAMENTS INSTITUT MALGACHE DE RECHERCHES APPLIQUEES (MG) 1997-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020051828-A1 Mixtures which can be isolated from eugenia jambolana lamarck seeds, their preparation and the use of these mixtures and some of their constituents as medicaments CMPK1, LNPK, SYMPK RIPK1 2487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.