SCHEMBL7560053

SCHEMBL7560053

CCCC(O)Cn1nnc2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
SLC9A1 P19634 7/20 0.59
RAB9A P51151 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
NPC1 O15118 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
MAPT P10636 6/20 0.58
LMNA P02545 3/20 0.58
TP53 P04637 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
HCRTR1 O43613 1/20 0.58
HTT P42858 1/20 0.58
APAF1 O14727 1/20 0.57
POLB P06746 1/20 0.57
GAA P10253 1/20 0.55
USP2 O75604 1/20 0.54
MDM2 Q00987 1/20 0.54
ALOX15 P16050 1/20 0.53
MAPK1 P28482 1/20 0.53
HSD17B10 Q99714 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL972935 0.84 APAF1 (0.62) ALDH1A1SLC9A1RAB9ASMN1; SMN2NPC1
SCHEMBL437789 0.83 ALDH1A1 (0.65) ALDH1A1SLC9A1RAB9ASMN1; SMN2NPC1
SCHEMBL11442537 0.81 APAF1 (0.68) ALDH1A1SLC9A1RAB9ASMN1; SMN2NPC1
SCHEMBL9772257 0.78 APAF1 (0.59) ALDH1A1SLC9A1RAB9ASMN1; SMN2NPC1
SCHEMBL7716431 0.77 APAF1 (0.67) ALDH1A1SLC9A1RAB9ASMN1; SMN2NPC1
SCHEMBL31702792 0.77 SLC9A1 (0.61) ALDH1A1SLC9A1RAB9ASMN1; SMN2NPC1
SCHEMBL5564842 0.76 SLC9A1 (0.64) ALDH1A1SLC9A1RAB9ASMN1; SMN2NPC1
SCHEMBL283896 0.75 SLC9A1 (1.00) ALDH1A1SLC9A1RAB9ANPC1MAPT
SCHEMBL22032189 0.75 SLC9A1 (0.50) ALDH1A1SLC9A1MAPTAPAF1POLB
SCHEMBL18571636 0.75 SLC9A1 (0.62) ALDH1A1SLC9A1RAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020174491-A1 Process for stabilizing the whiteness of lignin-containing fibrous materials, stabilizer composition and fibrous materials stabilized with this DEGUSSA-AG (DE) 2002-11-28 US claimed
EP-1241296-A2 Process for stabilizing brightness of lignin-containing fibrous material, a composition for stabilizing the brightness thereof and thus stabilized fibrous material Degussa AG (DE) 2002-09-18 EP claimed
US-4124564-A LIGHT AND HEAT RESISTANCE ARGUS CHEMICAL CORPORATION (US) 1978-11-07 US disclosed