Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1041780 | 0.96 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDALOX15CYP2D6 | |
| SCHEMBL1400955 | 0.96 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDALOX15CYP2D6 | |
| SCHEMBL5964463 | 0.96 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDALOX15CYP2D6 | |
| Zinc Ion SCHEMBL28885473 | 0.96 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDALOX15CYP2D6 | |
| Potassium Ion SCHEMBL3781302 | 0.96 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDALOX15CYP2D6 | |
| SCHEMBL28372305 | 0.96 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDALOX15CYP2D6 | |
| SCHEMBL143946 | 0.96 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDALOX15CYP2D6 | |
| Lithium Ion SCHEMBL7569829 | 0.92 | ALOX15 (0.49) | ALDH1A1KDM4EHPGDALOX15CYP2D6 | |
| Ethylene SCHEMBL4534559 | 0.92 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDALOX15CYP2D6 | |
| Potassium Ion SCHEMBL9845533 | 0.88 | ALOX15 (0.49) | ALDH1A1KDM4EHPGDALOX15CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115678377-B | Acrylic polyester resin and aqueous coating composition containing same | PPG工业俄亥俄公司 | 2024-05-28 | — | — | CN | claimed |
| CN-114404305-A | Dry-state mask with spontaneous heating function and preparation method thereof | 贺文祯 | 2022-04-29 | — | — | CN | claimed |
| CN-114259425-A | Preparation method of high-moisture-retention dry-state essence facial mask with temperature-sensitive absorption promoting function | 贺文祯 | 2022-04-01 | — | — | CN | claimed |
| EP-2366734-B9 | Polyamides and polyesters blended with a lithium salt interfacial tension reducing agent | M & G USA CORP (US) | 2017-08-16 | — | — | EP | claimed |
| EP-2366734-B1 | Polyamides and polyesters blended with a lithium salt interfacial tension reducing agent | M & G USA CORP (US) | 2017-02-01 | — | — | EP | claimed |
| US-20160040007-A1 | COMPOSITION FOR MAINTAINING GOOD COLOR WHEN THERMALLY TREATING POLYESTER-POLYAMIDE BLENDS | M&G USA CORPORATION (US) | 2016-02-11 | — | — | US | claimed |
| US-20140371402-A1 | POLYAMIDES AND POLYESTERS BLENDED WITH A LITHIUM SALT INTERFACIAL TENSION REDUCING AGENT | M&G USA CORPORATION | 2014-12-18 | — | — | US | claimed |
| CN-101321823-B | Polyamides and polyesters mixed with lithium salt interfacial tension reducing agents | M&G Polymer Italy Co.,Ltd. (IT) | 2012-02-22 | — | — | CN | claimed |
| EP-2366734-A1 | Polyamides and polyesters blended with a lithium salt interfacial tension reducing agent | M & G Polimeri Italia S.P.A. (IT) | 2011-09-21 | — | — | EP | claimed |
| EP-1931727-B1 | POLYAMIDES AND POLYESTERS BLENDED WITH A LITHIUM SALT INTERFACIAL TENSION REDUCING AGENT | M & G POLIMERI ITALIA SPA (IT) | 2011-07-27 | — | — | EP | claimed |
| EP-1951810-B1 | STABLE POLYAMIDES FOR SIMULTANEOUS SOLID PHASE POLYMERIZATION OF POLYESTERS AND POLYAMIDES | M & G POLIMERI ITALIA SPA (IT) | 2009-07-29 | — | — | EP | claimed |
| CN-101321823-A | Polyamides and polyesters mixed with lithium salt interfacial tension reducing agents | M & G POLIMERI ITALIA SPA (IT) | 2008-12-10 | — | — | CN | claimed |
| EP-1951810-A1 | STABLE POLYAMIDES FOR SIMULTANEOUS SOLID PHASE POLYMERIZATION OF POLYESTERS AND POLYAMIDES | M & G Polimeri Italia S.P.A. (IT) | 2008-08-06 | — | — | EP | claimed |
| EP-1931727-A1 | POLYAMIDES AND POLYESTERS BLENDED WITH A LITHIUM SALT INTERFACIAL TENSION REDUCING AGENT | M & G Polimeri Italia S.P.A. (IT) | 2008-06-18 | — | — | EP | claimed |
| WO-2007049233-A1 | STABLE POLYAMIDES FOR SIMULTANEOUS SOLID PHASE POLYMERIZATION OF POLYESTERS AND POLYAMIDES | M & G POLIMERI ITALIA S.P.A. (IT) | 2007-05-03 | — | — | WO | claimed |
| US-20070093616-A1 | Stable Polyamides For Simultaneous Solid Phase Polymerization of Polyesters and Polyamides | M&G USA CORPORATION | 2007-04-26 | — | — | US | claimed |
| WO-2007042230-A1 | POLYAMIDES AND POLYESTERS BLENDED WITH A LITHIUM SALT INTERFACIAL TENSION REDUCING AGENT | M & G POLIMERI ITALIA S.P.A. (IT) | 2007-04-19 | — | — | WO | claimed |
| US-20070082157-A1 | Polyamides and Polyesters Blended With A Lithium Salt Interfacial Tension Reducing Agent | M&G USA CORPORATION | 2007-04-12 | — | — | US | claimed |
| JP-59098130-A | — | — | None | — | — | JP | disclosed |
| JP-S5998130-A | PREPARATION OF MODIFIED POLYESTER | TORAY IND INC | 1984-06-06 | — | — | JP | disclosed |