Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548212 | 0.96 | ALOX15 (0.49) | ALOX15CYP2D6ALDH1A1KDM4EHPGD | |
| Lithium Ion SCHEMBL7569829 | 0.96 | ALOX15 (0.49) | ALOX15CYP2D6ALDH1A1KDM4EHPGD | |
| Potassium Ion SCHEMBL3781302 | 0.92 | ALDH1A1 (0.43) | ALOX15CYP2D6ALDH1A1KDM4EHPGD | |
| Terephthalic Acid SCHEMBL7867067 | 0.90 | ALOX15 (0.44) | ALOX15CYP2D6ALDH1A1KDM4EHPGD | |
| SCHEMBL5964463 | 0.88 | ALDH1A1 (0.43) | ALOX15CYP2D6ALDH1A1KDM4EHPGD | |
| SCHEMBL1041780 | 0.88 | ALDH1A1 (0.43) | ALOX15CYP2D6ALDH1A1KDM4EHPGD | |
| SCHEMBL1400955 | 0.88 | ALDH1A1 (0.43) | ALOX15CYP2D6ALDH1A1KDM4EHPGD | |
| SCHEMBL28372305 | 0.88 | ALDH1A1 (0.43) | ALOX15CYP2D6ALDH1A1KDM4EHPGD | |
| SCHEMBL143946 | 0.88 | ALDH1A1 (0.48) | ALOX15CYP2D6ALDH1A1KDM4EHPGD | |
| Zinc Ion SCHEMBL28885473 | 0.88 | ALDH1A1 (0.43) | ALOX15CYP2D6ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432489-A2 | Heat-adhesive composite fiber and nonwoven fabric made by using same | TEIJIN LIMITED (JP) | 1991-06-19 | — | — | EP | disclosed |