SCHEMBL143946

SCHEMBL143946

O=C([O-])c1cccc(C(=O)[O-])c1S(=O)(=O)O.[Na+].[Na+]

nearest known ligand 0.48

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 4/20 0.38
CA4 known ✓ P22748 1/20 0.38
CA1 known ✓ P00915 3/20 0.33
ALDH1A1 P00352 5/20 0.48
KDM4E B2RXH2 3/20 0.48
HPGD P15428 2/20 0.48
ALOX15 P16050 2/20 0.37
CYP2D6 P10635 2/20 0.35
PKLR P30613 1/20 0.35
TSHR P16473 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
POLB P06746 2/20 0.34
LMNA P02545 1/20 0.33
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33
HSD17B10 Q99714 2/20 0.32
NT5E P21589 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL4534559 0.96 ALDH1A1 (0.45) ALDH1A1KDM4EHPGDCA2CA4
Zinc Ion SCHEMBL28885473 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDCA2CA4
SCHEMBL1400955 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDCA2CA4
SCHEMBL28372305 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDCA2CA4
Potassium Ion SCHEMBL3781302 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDCA2CA4
SCHEMBL5964463 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDCA2CA4
SCHEMBL1041780 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDCA2CA4
Lithium Ion SCHEMBL756013 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDCA2CA4
SCHEMBL548212 0.92 ALOX15 (0.49) ALDH1A1KDM4EHPGDCA2CA4
SCHEMBL31552763 0.91 KDM4E (0.41) ALDH1A1KDM4EHPGDCA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3148 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4200373-B1 BREATHABLE COMPOSITE POLYMERIC FILMS MYLAR SPECIALTY FILMS U S LP (US) 2026-01-07 EP claimed
EP-4663685-A1 METHOD FOR PRODUCING COPOLYMER POLYESTER RESIN TOYOBO MC Corporation (JP) 2025-12-17 EP claimed
EP-4596601-A1 CO-POLYESTER RESIN TOYOBO MC Corporation (JP) 2025-08-06 EP claimed
EP-4596602-A1 CO-POLYESTER RESIN TOYOBO MC Corporation (JP) 2025-08-06 EP claimed
US-20250197563-A1 COPOLYMERIZED POLYESTER RESIN TOYOBO MC CORPORATION (JP) 2025-06-19 US claimed
CN-119968418-A Copolyester resin 东洋纺艾睦希株式会社 2025-05-09 CN claimed
CN-119816539-A Copolyester resin 东洋纺艾睦希株式会社 2025-04-11 CN claimed
EP-4512844-A1 COPOLYMER POLYESTER RESIN TOYOBO MC Corporation (JP) 2025-02-26 EP claimed
CN-119283407-A Transparent weather-resistant glass fiber reinforced thermoplastic matrix composite material and preparation method thereof 河南工业大学 2025-01-10 CN claimed
CN-119137184-A Copolyester resin 东洋纺艾睦希株式会社 2024-12-13 CN claimed
EP-0651090-A1 Suede-like artificial leather Kuraray Co., Ltd. (JP) 1995-05-03 EP claimed
EP-0364331-B1 Water-dissipatable polyester resins and coatings prepared therefrom EASTMAN KODAK CO (US) 1994-06-08 EP claimed
EP-0132951-B2 Polyester film and magnetic recording medium made therefrom TORAY INDUSTRIES (JP) 1994-05-25 EP claimed
EP-0588313-A1 Silver halide color photosensitive material KONICA CORPORATION (JP) 1994-03-23 EP claimed
US-4990593-A Curable with amino resin; waterproof enamel; polyesteramides from aminocarboxylic acids, amino alcohols, sulfonated acids, glycols, diamines EASTMAN KODAK COMPANY (US) 1991-02-05 US claimed
US-4910292-A Having carbonyloxy linking groups EASTMAN KODAK COMPANY (US) 1990-03-20 US claimed
EP-0132951-B1 POLYESTER FILM AND MAGNETIC RECORDING MEDIUM MADE THEREFROM TORAY INDUSTRIES, INC. (JP) 1986-11-26 EP claimed
US-4590119-A ORIENTED FILM CONTAINING FINE PARTICLES AND FATTY ACID OR FATTY ESTER; SLIDING; FLATNESS; ADHESION; DISKS; TAPES TORAY INDUSTRIES, INC. (JP) 1986-05-20 US claimed
EP-0132951-A1 Polyester film and magnetic recording medium made therefrom TORAY INDUSTRIES, INC. (JP) 1985-02-13 EP claimed
US-4052368-A WATER-DISPELLABLE HOT MELT POLYESTER ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-10-04 US claimed