Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562364 | 0.81 | CYP11B1 (0.35) | POLBKDM4EGAAMEN1KMT2A | |
| SCHEMBL7560334 | 0.81 | POLB (0.39) | POLBMEN1KMT2A | |
| SCHEMBL5265951 | 0.78 | POLB (0.44) | POLBMEN1KMT2A | |
| SCHEMBL4078455 | 0.75 | KDR (0.44) | KDM4E | |
| SCHEMBL8312119 | 0.73 | POLB (0.40) | POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9051187 | 0.73 | CHRM2 (0.38) | POLBSLC6A2SLC6A4 | |
| SCHEMBL6961333 | 0.72 | POLB (0.39) | POLBMEN1KMT2A | |
| SCHEMBL7444323 | 0.72 | POLB (0.41) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5543765 | 0.72 | POLB (0.39) | POLBMEN1KMT2A | |
| SCHEMBL7562738 | 0.72 | POLB (0.36) | POLBSLC6A2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999065487-A1 | INHIBITORS OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |