Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969006 | 0.86 | ADORA2A (0.41) | POLBKMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL5265951 | 0.81 | POLB (0.44) | POLBKMT2AMEN1 | |
| SCHEMBL5543765 | 0.75 | POLB (0.39) | POLBKMT2AMEN1NOS1NOS2 | |
| SCHEMBL7560334 | 0.75 | POLB (0.39) | POLBKMT2AMEN1 | |
| SCHEMBL6961333 | 0.75 | POLB (0.39) | POLBKMT2AMEN1 | |
| SCHEMBL7444323 | 0.75 | POLB (0.41) | POLBKMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL6683579 | 0.73 | POLB (0.37) | POLBKMT2AMEN1 | |
| SCHEMBL8368017 | 0.73 | SLC6A3 (0.37) | POLBKMT2AALDH1A1MEN1 | |
| SCHEMBL10374921 | 0.73 | HCRTR1 (0.37) | — | |
| SCHEMBL7561336 | 0.72 | MEN1 (0.41) | KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925288-A1 | PROCESS OF PRODUCTION OF 4-SUBSTITUTED-3-HALOGENO-1,4-BENZOXAZEPINE DERIVATIVE AND SALTS THEREOF | SUNTORY LIMITED (JP) | 1999-06-30 | — | — | EP | disclosed |
| WO-1999003847-A1 | PROCESS OF PRODUCTION OF 4-SUBSTITUTED-3-HALOGENO-1,4-BENZOXAZEPINE DERIVATIVE AND SALTS THEREOF | SUNTORY LIMITED (JP) | 1999-01-28 | — | — | WO | disclosed |