Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005130 | 0.91 | TP53 (0.35) | MEN1KMT2ABRD4 | |
| SCHEMBL7183643 | 0.88 | TP53 (0.33) | KMT2AMCHR1BRD4KDM4E | |
| SCHEMBL7004596 | 0.85 | PTGER1 (0.39) | PTGER1PTGER4PTGER3PTGER2PTPN1 | |
| SCHEMBL7003666 | 0.81 | PPARG (0.41) | PTGER1PTGER4PTGER3PTGER2KDM4E | |
| SCHEMBL7556767 | 0.81 | DPP4 (0.37) | BRD4 | |
| SCHEMBL7003191 | 0.77 | HPGD (0.41) | PTGER1PTGER4PTGER3PTGER2PTPN1 | |
| SCHEMBL7004236 | 0.75 | MMP2 (0.43) | PTGER1 | |
| SCHEMBL7556080 | 0.74 | CRHBP (0.43) | PTGER1PTGER4PTGER3PTGER2PTPN1 | |
| SCHEMBL7002021 | 0.73 | NR1H4 (0.33) | PTPN1PTGESABCB1MCHR1 | |
| SCHEMBL5238084 | 0.69 | DPP4 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062764-A9 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-10 | — | — | WO | disclosed |