Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.67 |
| ▸ | CTSK | P43235 | 16/20 | 0.67 |
| ▸ | CTSL | P07711 | 13/20 | 0.67 |
| ▸ | CTSB | P07858 | 12/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560363 | 0.90 | CTSS (0.64) | CTSSCTSKCTSLCTSBHTT | |
| SCHEMBL7537053 | 0.81 | CTSS (1.00) | CTSSCTSKCTSLCTSB | |
| SCHEMBL7534180 | 0.79 | CTSS (0.52) | CTSSCTSKCTSLCTSB | |
| Hydrochloric Acid SCHEMBL7561368 | 0.75 | HDAC8 (0.51) | CTSSCTSKCTSLCTSBKCNH2 | |
| Hydrochloric Acid SCHEMBL7561355 | 0.75 | HDAC8 (0.51) | CTSSCTSKCTSLCTSBKCNH2 | |
| SCHEMBL7569060 | 0.75 | CTSS (1.00) | CTSSCTSKCTSLCTSB | |
| SCHEMBL7534190 | 0.70 | CTSK (0.91) | CTSSCTSKCTSLCTSB | |
| SCHEMBL7531501 | 0.70 | CTSS (1.00) | CTSSCTSKCTSLCTSB | |
| SCHEMBL7531656 | 0.69 | FAAH (0.43) | CTSSCTSK | |
| SCHEMBL7537367 | 0.69 | CTSK (0.42) | CTSSCTSKCTSLCTSBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |