Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647908 | 0.78 | CTSL (0.68) | CTSKCTSLCTSBCTSS | |
| SCHEMBL7528404 | 0.78 | CTSL (0.35) | CTSKCTSLCTSBCTSSCES1 | |
| SCHEMBL7560363 | 0.78 | CTSS (0.64) | CTSKCTSLCTSBCTSSHTT | |
| SCHEMBL7537370 | 0.73 | POLB (0.40) | CTSKCTSLCTSBCTSSHDAC8 | |
| SCHEMBL7533228 | 0.72 | DAGLA (0.50) | CTSSHDAC8CES1HDAC1HDAC6 | |
| SCHEMBL7530434 | 0.72 | DAGLA (0.52) | HDAC8CES1HDAC1HDAC6FAAH | |
| SCHEMBL7537340 | 0.70 | CTSL (0.66) | CTSKCTSLCTSBCTSSCES1 | |
| SCHEMBL7560369 | 0.69 | CTSS (0.67) | CTSKCTSLCTSBCTSSHTT | |
| SCHEMBL30968135 | 0.68 | NPC1 (0.61) | HDAC8KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL30968155 | 0.67 | SMPD1 (0.61) | HDAC8KMT2AKDM4EALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |