Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.53 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16425772 | 0.84 | MAOA (0.55) | HTR2AACHECYP1A2MAOATSHR | |
| SCHEMBL12658227 | 0.81 | — | — | |
| SCHEMBL14870745 | 0.76 | HTR2A (0.55) | HTR2ANOS3NOS2ACHEHRH1 | |
| SCHEMBL29439854 | 0.76 | HTR2A (0.55) | HTR2ANOS3NOS2ACHEHRH1 | |
| SCHEMBL8941781 | 0.74 | ACHE (0.59) | HTR2ANOS3NOS2ACHEHTR2C | |
| SCHEMBL13781664 | 0.74 | HTR2A (0.53) | HTR2ANOS3NOS2ACHETSHR | |
| SCHEMBL4748664 | 0.74 | HTR2A (0.58) | HTR2ANOS3NOS2ACHEHRH1 | |
| SCHEMBL4464634 | 0.74 | ACHE (0.39) | HTR2ANOS3NOS2ACHEMAOA | |
| SCHEMBL20690706 | 0.74 | HTR2A (0.53) | HTR2ANOS3NOS2ACHETSHR | |
| SCHEMBL29865183 | 0.74 | ACHE (0.59) | HTR2AACHEMAOAHRH1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142855-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2012-06-07 | — | — | US | disclosed |
| EP-0946473-B1 | FLUORINATED PHENANTRENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECHNOLOGY GMBH (DE) | 2002-07-31 | — | — | EP | disclosed |
| US-6168838-B1 | FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICE | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2001-01-02 | — | — | US | disclosed |
| EP-0946473-A1 | FLUORINATED PHENANTRENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | Aventis Research & Technologies GmbH & Co. KG. (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027035-A1 | FLUORINATED PHENANTRENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142855-A1 | MATERIALS FOR ELECTRONIC DEVICES | PEF1, PARG, EFNA1 | HTR2A 3810/4885NOS3 1615/4885NOS2 1770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.