Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5918049 | 0.98 | PPARG (0.44) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5917972 | 0.87 | PPARG (0.36) | PPARGPPARACYP2C9KMT2AMEN1 | |
| SCHEMBL77404 | 0.86 | NPC1 (0.40) | PPARGPPARACYP2C9KMT2AMEN1 | |
| SCHEMBL76511 | 0.84 | PPARG (0.37) | PPARGPPARACYP2C9KMT2AMEN1 | |
| SCHEMBL76267 | 0.83 | L3MBTL1 (0.44) | KMT2AMEN1 | |
| SCHEMBL85757 | 0.81 | PPARG (0.35) | PPARGPPARACYP2C9KMT2AMEN1 | |
| SCHEMBL24327737 | 0.78 | PPARG (0.49) | PPARGPPARACYP2C9KMT2AMEN1 | |
| SCHEMBL76084 | 0.75 | LMNA (0.38) | CYP2C9KMT2AMEN1CYP2C19LMNA | |
| SCHEMBL9291604 | 0.74 | SLC6A2 (0.50) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL77607 | 0.74 | TSHR (0.39) | CYP2C9CYP2D6CYP2C19LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919857-B1 | PROCESS FOR THE SYNTHESIS OF MANDIPROPAMID AND DERIVATIVES THEREOF | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-09 | — | — | EP | disclosed |
| EP-1919857-B1 | PROCESS FOR THE SYNTHESIS OF MANDIPROPAMID AND DERIVATIVES THEREOF | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-09 | — | — | EP | disclosed |
| US-8501993-B2 | Processes for the preparation of amides | SYNGENTA LIMITED (GB) | 2013-08-06 | — | — | US | disclosed |
| US-8501993-B2 | Processes for the preparation of amides | SYNGENTA LIMITED (GB) | 2013-08-06 | — | — | US | disclosed |
| US-8129560-B2 | Process for the synthesis of mandipropamid and derivatives thereof | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129560-B2 | Process for the synthesis of mandipropamid and derivatives thereof | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129560-B2 | Process for the synthesis of mandipropamid and derivatives thereof | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110071315-A1 | PROCESSES FOR THE PREPARATION OF AMIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-03-24 | — | — | US | disclosed |
| US-20110071315-A1 | PROCESSES FOR THE PREPARATION OF AMIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-03-24 | — | — | US | disclosed |
| WO-2009138372-A1 | PROCESSES FOR THE PREPARATION OF AMIDES | SYNGENTA LIMITED (GB) | 2009-11-19 | — | — | WO | disclosed |
| US-20090118532-A1 | Process for the Synthesis of Mandipropamid and Derivatives Thereof | SYNGENTA CROP PROTECTION, INC. (US) | 2009-05-07 | — | — | US | disclosed |
| EP-1919857-A2 | PROCESS FOR THE SYNTHESIS OF MANDIPROPAMID AND DERIVATIVES THEREOF | Syngeta Participations AG (CH) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007020381-A2 | PROCESS FOR THE SYNTHESIS OF MANDIPROPAMID AND DERIVATIVES THEREOF | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007020381-A2 | PROCESS FOR THE SYNTHESIS OF MANDIPROPAMID AND DERIVATIVES THEREOF | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
| US-7166746-B2 | N-bisaryl- and n-aryl-cycloakylidenyl-αhydroxy-and α-alkoxy acid amides | SYNGENTA CROP PROTECTION, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-20060041144-A1 | Phenylpyridine compound and fungicidal compostion containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-02-23 | — | — | US | disclosed |
| US-20050245607-A1 | N-bisaryl- and n-aryl-cylcloakylidenyl-alpha-hydroxy-and alpha-alkoxy acid amides | SYNGENTA CROP PROTECTION, INC. | 2005-11-03 | — | — | US | disclosed |
| EP-1541557-A1 | PHENYLPYRIDINE COMPOUND AND BACTERICIDAL COMPOSITION CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-1534664-A1 | N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY-AND ALPHA-ALKOXY ACID AMIDES | Syngenta Participations AG (CH) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004011417-A1 | N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY-AND ALPHA-ALKOXY ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071315-A1 | PROCESSES FOR THE PREPARATION OF AMIDES | PAH, CYP3A4, AKR7A2 | PPARG 777/4885PPARA 620/4885SLC1A3 1181/4885 |
| US-20060041144-A1 | Phenylpyridine compound and fungicidal compostion containing the same | CBR3, CYP1A1, PAH | PPARG 2437/4885PPARA 3189/4885SLC1A3 4516/4885 |
| US-20050245607-A1 | N-bisaryl- and n-aryl-cylcloakylidenyl-alpha-hydroxy-and alpha-alkoxy acid amides | CBR3, CBR1, AKR1C3 | PPARG 1695/4885PPARA 2137/4885SLC1A3 2037/4885 |
| US-20090118532-A1 | Process for the Synthesis of Mandipropamid and Derivatives Thereof | OPRM1, OPRD1, ADRA1D | PPARG 4173/4885PPARA 3458/4885SLC1A3 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.