Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | CTSV | O60911 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174291 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL7562120 | 0.75 | ALDH1A1 (0.31) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL6176009 | 0.68 | OPRK1 (0.33) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL6175249 | 0.66 | MLNR (0.41) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL18511473 | 0.63 | ESR1 (0.46) | KDM4EGAAOPRM1SLC22A1 | |
| SCHEMBL6188801 | 0.63 | SLC22A1 (0.34) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL6172879 | 0.60 | HSD11B1 (0.35) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL25210900 | 0.59 | CYP17A1 (0.55) | KDM4EALDH1A1GAAHSD17B10OPRM1 | |
| SCHEMBL27514771 | 0.59 | SLC22A1 (0.57) | KDM4EALDH1A1GAAHSD17B10OPRM1 | |
| SCHEMBL2498400 | 0.57 | ALDH1A1 (0.40) | KDM4EALDH1A1GAAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-B1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | UPJOHN CO (US) | 2002-09-11 | — | — | EP | disclosed |