Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | FABP3 | P05413 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL20573708 | 1.00 | NFKB1 (0.50) | NFKB1GPR84BBOX1CA1FABP3 | |
| SCHEMBL20573580 | 0.96 | NFKB1 (0.55) | NFKB1GPR84BBOX1CA1FABP3 | |
| SCHEMBL31618774 | 0.96 | NFKB1 (0.55) | NFKB1GPR84BBOX1CA1FABP3 | |
| Zinc Ion SCHEMBL8112924 | 0.96 | NFKB1 (0.50) | NFKB1GPR84BBOX1CA1FABP3 | |
| SCHEMBL11688874 | 0.86 | NFKB1 (0.59) | NFKB1GPR84BBOX1CA1 | |
| Potassium Ion SCHEMBL25191979 | 0.84 | CA1 (0.62) | NFKB1GPR84BBOX1CA1FABP3 | |
| Potassium Ion SCHEMBL3744114 | 0.84 | CA1 (0.50) | NFKB1GPR84BBOX1CA1FABP3 | |
| Potassium Ion SCHEMBL5277730 | 0.84 | CA1 (0.62) | NFKB1GPR84BBOX1CA1FABP3 | |
| Potassium Ion SCHEMBL31561784 | 0.84 | CA1 (0.62) | NFKB1GPR84BBOX1CA1FABP3 | |
| Potassium Ion SCHEMBL11652127 | 0.84 | CA1 (0.62) | NFKB1GPR84BBOX1CA1FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808625-B1 | External skin-care composition | KAO CORP (JP) | 2002-08-07 | — | — | EP | disclosed |
| EP-0808625-A1 | External skin-care composition | Kao Corporation (JP) | 1997-11-26 | — | — | EP | disclosed |