Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227201 | 0.80 | LTA4H (0.50) | MAPK1TP53 | |
| SCHEMBL1326408 | 0.77 | TP53 (0.41) | MAPK1MMP1MMP9MMP12TP53 | |
| SCHEMBL28304831 | 0.75 | ALDH1A1 (0.47) | MAPK1TP53 | |
| SCHEMBL28304719 | 0.75 | LTA4H (0.50) | MAPK1 | |
| SCHEMBL8863814 | 0.75 | SOS1 (0.37) | — | |
| SCHEMBL28304760 | 0.75 | MAOA (0.43) | TP53 | |
| SCHEMBL28304731 | 0.73 | LTA4H (0.43) | MAPK1TP53 | |
| Furan SCHEMBL16198063 | 0.71 | TDP1 (0.38) | MAPK1MMP1MMP9MMP12TP53 | |
| SCHEMBL609237 | 0.71 | LTA4H (0.44) | — | |
| SCHEMBL8498303 | 0.71 | ALDH1A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882703-B1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6011174-A | INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENT ANTITUMOR ACTIVITIES, | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0882703-A1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |