SCHEMBL3227201

SCHEMBL3227201

c1ccc(Oc2ccco2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.50
TSHR P16473 2/20 0.50
MAPK1 P28482 1/20 0.45
LMNA P02545 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
NR1H2 P55055 1/20 0.39
BAX Q07812 1/20 0.39
MAOA P21397 1/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 1/20 0.39
MAPT P10636 4/20 0.37
HTT P42858 3/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1326408 0.82 TP53 (0.41) TSHRMAPK1LMNASMN1; SMN2TP53
SCHEMBL7562902 0.80 MAPK1 (0.32) MAPK1TP53
SCHEMBL8863814 0.80 SOS1 (0.37) LTA4HLMNAMAOAALDH1A1HPGD
SCHEMBL8498303 0.76 ALDH1A1 (0.49) LMNASMN1; SMN2ALDH1A1MAPTNPC1
SCHEMBL8497843 0.76 LTA4H (0.55) LTA4HTSHRMAPK1LMNASMN1; SMN2
SCHEMBL1372293 0.72
Furan SCHEMBL16198063 0.71 TDP1 (0.38) MAPK1LMNATP53ALDH1A1HPGD
SCHEMBL5210323 0.70 TP53 (0.36) LMNATP53ALDH1A1HPGDMAPT
SCHEMBL19662081 0.70 TAAR1 (0.53) LTA4HTSHRLMNASMN1; SMN2TP53
Diphenylether SCHEMBL9061108 0.69 LTA4H (1.00) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102762630-A Green soluble conjugated polymers with high carrier mobility UNIV FLORIDA 2012-10-31 CN claimed
CN-117776902-A Preparation method of naproxen 帕潘纳(北京)科技有限公司 2024-03-29 CN disclosed
CN-116726178-A Use of sGC stimulators in the treatment of non-alcoholic steatohepatitis (NASH) 赛克里翁治疗有限公司 2023-09-12 CN disclosed
CN-109706133-B Novel esterase and application thereof 上海交通大学 2022-12-27 CN disclosed
CN-109627360-B Agglomerated propylene containing thermally reversible crosslinking group and preparation method thereof 江苏中煦聚烯烃研究院有限公司 2021-04-09 CN disclosed
CN-106632168-A Synthetic method of lactate derivative as well as product and application thereof 上海生农生化制品股份有限公司 2017-05-10 CN disclosed
CN-102762630-A Green soluble conjugated polymers with high carrier mobility UNIV FLORIDA 2012-10-31 CN disclosed
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 US disclosed
US-4551476-A 13,14-Didehydro-prostaglandins and process for their preparation FARMITALIA CARLO ERBA S.P.A. (IT) 1985-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041694-A1 AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES HDHD5, NAAA, BROX LTA4H 1920/4885TSHR 4380/4885MAPK1 2539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.