Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12667381 | 0.86 | KMT2A (0.58) | KMT2ARAB9AMEN1LMNASMN1; SMN2 | |
| SCHEMBL14099677 | 0.83 | HDAC8 (0.56) | RAB9AF10NPC1 | |
| SCHEMBL2277217 | 0.82 | KMT2A (0.54) | KMT2ARAB9AMAPTNPSR1MEN1 | |
| SCHEMBL7427631 | 0.82 | CES2 (0.67) | KMT2ARAB9ANPSR1MEN1SMN1; SMN2 | |
| SCHEMBL16587854 | 0.81 | ALOX15 (0.47) | KMT2AMAPTMEN1LMNAGAA | |
| Hydrochloric Acid SCHEMBL28773319 | 0.81 | F10 (0.47) | KMT2ARAB9AMAPTNPSR1MEN1 | |
| SCHEMBL14519864 | 0.81 | LMNA (0.58) | KMT2ARAB9AMAPTMEN1LMNA | |
| SCHEMBL16950311 | 0.80 | KMT2A (0.51) | KMT2ARAB9AMAPTNPSR1MEN1 | |
| SCHEMBL30744738 | 0.80 | MRGPRX4 (0.63) | KMT2ARAB9AMAPTNPSR1MEN1 | |
| SCHEMBL11381012 | 0.80 | ALOX15 (0.58) | KMT2ARAB9AMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959742-B1 | FUNGICIDAL COMPOSITION CONTAINING CARBOXYLIC ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA (JP) | 2016-11-02 | — | — | EP | disclosed |
| US-8420572-B2 | Fungicidal composition containing carboxylic acid amide derivative | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2013-04-16 | — | — | US | disclosed |
| EP-1776011-B1 | FUNGICIDAL COMPOSITION CONTAINING AN ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-8039420-B2 | Fungicidal composition containing acid amide derivative | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| US-7829501-B2 | Fungicidal composition containing acid amide derivative | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20100261735-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20100261675-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20100222337-A1 | FUNGICIDAL COMPOSITION CONTAINING CARBOXYLIC ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-09-02 | — | — | US | disclosed |
| US-20080318779-A1 | N-[(4'-methoxy-2'-methyl-1,1-dimethyl)phenacyl]-3-methyl-2-thiophenecarboxamide and another fungicide or an antibiotic; controlling noxious fungi at a low dose; Oomycetes, Ascomycetes, Basidiomycetes, Deuteromycetes particularly effective against Ascomycetes or Deuteromycetes; plant diseases | ISHIHARA SANGYO KAISHA LTD (JP) | 2008-12-25 | — | — | US | disclosed |
| CN-101330831-A | Bactericidal composition comprising carboxylic acid amide derivative | ISHIHARA SANGYO KAISHA (JP) | 2008-12-24 | — | — | CN | disclosed |
| EP-1959742-A2 | FUNGICIDAL COMPOSITION CONTAINING CARBOXYLIC ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2008-08-27 | — | — | EP | disclosed |
| US-20080200465-A1 | Substituted with a morpholine group through amido heterocylic groups; interfering with the expression of genes essential for the pathogen's proliferation; treating viral and protozoan infections in mammals | GENESOFT PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-7348427-B2 | Antipathogenic benzamide compounds | GENESOFT PHARMACEUTICALS, INC. (US) | 2008-03-25 | — | — | US | disclosed |
| WO-2007069777-A2 | FUNGICIDAL COMPOSITION CONTAINING CARBOXYLIC ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2007-06-21 | — | — | WO | disclosed |
| EP-1776011-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006016708-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200465-A1 | Substituted with a morpholine group through amido heterocylic groups; interfering with the expression of genes essential for the pathogen's proliferation; treating viral and protozoan infections in mammals | IRF3, BCL3, L3MBTL3 | KMT2A 1133/4885RAB9A 2417/4885MAPT 4789/4885 |
| US-20100222337-A1 | FUNGICIDAL COMPOSITION CONTAINING CARBOXYLIC ACID AMIDE DERIVATIVE | CNPY2, CBR3, ACOX3 | KMT2A 2680/4885RAB9A 1842/4885MAPT 4475/4885 |
| US-20080318779-A1 | N-[(4'-methoxy-2'-methyl-1,1-dimethyl)phenacyl]-3-methyl-2-thiophenecarboxamide and another fungicide or an antibiotic; controlling noxious fungi at a low dose; Oomycetes, Ascomycetes, Basidiomycetes, Deuteromycetes particularly effective against Ascomycetes or Deuteromycetes; plant diseases | AADAC, NAT1, TH | KMT2A 237/4885RAB9A 2846/4885MAPT 3270/4885 |
| US-20100261675-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | CBR3, AADAC, NAT1 | KMT2A 818/4885RAB9A 2222/4885MAPT 4148/4885 |
| US-20100261735-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | CBR3, AADAC, NAT1 | KMT2A 818/4885RAB9A 2222/4885MAPT 4148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.