Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 5/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | WNT1 | P04628 | 3/20 | 0.32 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760502 | 0.82 | FFAR1 (0.38) | GPR142FAAHGAAPIK3CDHCRTR1 | |
| SCHEMBL759900 | 0.81 | FAAH (0.44) | GPR142FAAHNAAA | |
| SCHEMBL765578 | 0.79 | KEAP1 (0.42) | GPR142MGLLDYRK1APIK3CDHCRTR1 | |
| SCHEMBL759673 | 0.74 | MAPT (0.43) | FAAH | |
| SCHEMBL782217 | 0.73 | GPR119 (0.38) | GPR142GAAPIK3CDHCRTR1HCRTR2 | |
| SCHEMBL765579 | 0.73 | LMNA (0.51) | GPR142GAA | |
| SCHEMBL758615 | 0.71 | TDP1 (0.45) | FAAH | |
| SCHEMBL781918 | 0.71 | FAAH (0.39) | GPR142FAAHNAAA | |
| SCHEMBL782067 | 0.70 | BACE1 (0.38) | GPR142MGLLFAAH | |
| SCHEMBL760249 | 0.67 | LMNA (0.37) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431360-B1 | Derivatives of dihydrobenzoxathiazepine, method of preparing same and pharmaceutical compositions containing them as well as their uses as modulators of AMPA receptors | SERVIER LAB (FR) | 2013-04-17 | — | — | EP | disclosed |
| EP-2431360-A1 | Derivatives of dihydrobenzoxathiazepine, method of preparing same and pharmaceutical compositions containing them as well as their uses as modulators of AMPA receptors | Les Laboratoires Servier (FR) | 2012-03-21 | — | — | EP | disclosed |