Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476351 | 0.78 | KEAP1 (0.70) | KEAP1NFE2L2NPC1RAB9APTGS1 | |
| SCHEMBL11516751 | 0.77 | KEAP1 (0.68) | KEAP1NFE2L2NPC1RAB9APTGS1 | |
| SCHEMBL9355162 | 0.77 | GAA (0.62) | GAAKDM4ETDP1NPC1RAB9A | |
| SCHEMBL28435446 | 0.76 | ALDH1A1 (0.65) | GAAKDM4ETDP1KEAP1NFE2L2 | |
| SCHEMBL21602332 | 0.75 | KEAP1 (0.68) | GAAKDM4EKEAP1NPC1RAB9A | |
| SCHEMBL11709570 | 0.71 | ALDH1A1 (0.56) | GAAKDM4ETDP1KEAP1NFE2L2 | |
| SCHEMBL1853767 | 0.71 | KEAP1 (0.60) | GAAKDM4ETDP1KEAP1NPC1 | |
| SCHEMBL21811382 | 0.71 | ALDH1A1 (0.51) | GAAKDM4ETDP1KEAP1NFE2L2 | |
| SCHEMBL2467696 | 0.70 | GAA (0.56) | GAAKDM4ETDP1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5894060 | 0.70 | KEAP1 (0.58) | GAAKDM4ETDP1KEAP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1231889-A2 | DIRECT HAIR DYES AND USE THEREOF | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001026615-A2 | DIRECT HAIR DYES CONTAINING A HYDROXYANTHROQUINONE DERIVATIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-04-19 | — | — | WO | disclosed |